SCHEMBL11565621

SCHEMBL11565621

CC(C)Oc1ccc(NC(=O)C2(C)CC2)cc1F

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNQ3 O43525 1/20 0.47
KCNQ2 O43526 1/20 0.47
RORC P51449 1/20 0.46
BRAF P15056 1/20 0.44
KDR P35968 1/20 0.44
BACE1 P56817 1/20 0.44
P2RX3 P56373 10/20 0.44
FFAR1 O14842 2/20 0.43
EPHX2 P34913 1/20 0.42
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MET P08581 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11049200 0.90 MEN1 (0.44) BRAFKDRBACE1FFAR1EPHX2
SCHEMBL11563744 0.88 FFAR1 (0.43) BRAFKDRBACE1FFAR1EPHX2
SCHEMBL11435252 0.85 RORC (0.47) RORCP2RX3NPC1ALDH1A1TP53
SCHEMBL11564649 0.84 RORC (0.46) RORCBACE1P2RX3NPC1ALDH1A1
SCHEMBL11049020 0.84 RORC (0.67) RORCP2RX3NPC1ALDH1A1TP53
SCHEMBL26075853 0.84 MET (0.58) KDRMET
SCHEMBL11564073 0.84 RXRA (0.48) RORCBRAFKDRP2RX3EPHX2
SCHEMBL11565021 0.84 MET (0.49) BRAFKDRBACE1P2RX3FFAR1
SCHEMBL11442327 0.83 RORC (0.45) RORCBACE1P2RX3NPC1ALDH1A1
SCHEMBL26074436 0.83 MET (0.59) KCNQ3KCNQ2KDRP2RX3MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4166735-A Cycloalkanecarboxanilide derivative herbicides SHELL OIL COMPANY (US) 1979-09-04 US disclosed