Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11050893 | 0.88 | SMN1; SMN2 (0.42) | NPC1ALDH1A1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL11435252 | 0.85 | RORC (0.47) | RORCNPC1ALDH1A1RAB9ATP53 | |
| SCHEMBL11049020 | 0.84 | RORC (0.67) | RORCNPC1ALDH1A1RAB9ATP53 | |
| SCHEMBL11565621 | 0.84 | KCNQ3 (0.47) | RORCNPC1ALDH1A1RAB9ATP53 | |
| SCHEMBL11566980 | 0.84 | SMN1; SMN2 (0.41) | NPC1RAB9ATP53SMN1; SMN2HDAC1 | |
| SCHEMBL11442327 | 0.83 | RORC (0.45) | RORCNPC1ALDH1A1RAB9ATP53 | |
| SCHEMBL11565436 | 0.82 | HDAC1 (0.39) | NPC1ALDH1A1RAB9AHDAC1MAPT | |
| SCHEMBL11564073 | 0.81 | RXRA (0.48) | RORCNPC1ALDH1A1RAB9ATP53 | |
| SCHEMBL11558200 | 0.77 | CETP (0.41) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL11562238 | 0.76 | KDM4E (0.39) | RORCNPC1ALDH1A1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166735-A | Cycloalkanecarboxanilide derivative herbicides | SHELL OIL COMPANY (US) | 1979-09-04 | — | — | US | disclosed |