Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499284 | 0.78 | PNMT (0.52) | PNMTIDO1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL11565773 | 0.77 | PNMT (0.51) | PNMTIDO1TAAR1 | |
| SCHEMBL4419129 | 0.76 | PNMT (0.53) | PNMTIDO1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL26649158 | 0.73 | PNMT (0.59) | PNMTIDO1MAOBTAAR1SLC6A2 | |
| SCHEMBL29609180 | 0.72 | IDO1 (0.52) | PNMTIDO1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL2308 | 0.72 | IDO1 (0.52) | PNMTIDO1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL8893657 | 0.71 | PNMT (0.68) | PNMTIDO1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL14846267 | 0.70 | IGF1R (0.53) | PNMTIDO1TAAR1SIGMAR1IGF1R | |
| SCHEMBL14829408 | 0.69 | IGF1R (0.56) | PNMTIDO1TAAR1SIGMAR1IGF1R | |
| SCHEMBL26004833 | 0.69 | PNMT (0.64) | PNMTIDO1TAAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145362-A | DIAZOTIZATION OF ARYLAMINE IN PRESENCE OF ALKANOIC ACID, COPPER HALIDE CATALYST | S.A. P R B EN NEERLANDAIS PRB N.V. (BE) | 1979-03-20 | — | — | US | disclosed |