SCHEMBL11565823

SCHEMBL11565823

C=CCc1ccc(C(=O)c2ccccc2O)c(O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.54
CYP3A4 P08684 3/20 0.49
HPGD P15428 2/20 0.49
AR P10275 2/20 0.49
ALOX15 P16050 2/20 0.49
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49
PGR P06401 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
CHRM1 P11229 1/20 0.49
TBXA2R P21731 1/20 0.49
SLC6A2 P23975 1/20 0.49
CYP2C19 P33261 1/20 0.49
ADRA1A P35348 1/20 0.49
HIF1A Q16665 1/20 0.49
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
GABRA1 P14867 3/20 0.49
GABRB2 P47870 3/20 0.49
ALDH1A1 P00352 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL680148 0.92 XDH (0.63) XDHCYP3A4HPGDARCYP1A2
SCHEMBL9495776 0.86 MEN1 (0.57) XDHCYP3A4HPGDARLMNA
SCHEMBL977495 0.80 XDH (0.61) XDHCYP3A4HPGDARMEN1
SCHEMBL526114 0.80 TDP1 (0.52) XDHCYP3A4HPGDARALOX15
SCHEMBL11244618 0.79 GSTA1 (0.45) CYP3A4HPGDARALOX15LMNA
SCHEMBL9246348 0.79 XDH (0.59) XDHCYP3A4HPGDARMEN1
SCHEMBL5831660 0.79 XDH (0.59) XDHCYP3A4HPGDARCYP1A2
Zinc Ion SCHEMBL9246345 0.78 XDH (0.58) XDHCYP3A4HPGDARMEN1
Chavicol SCHEMBL11490954 0.75 ALDH1A1 (0.56) XDHCYP3A4HPGDALOX15LMNA
Salicylic Acid SCHEMBL3435070 0.74 ALDH1A1 (0.60) XDHCYP3A4HPGDALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4177122-A ETHERIFICATION WITH AN ALKYLENE OXIDE FOLLOWED BY ESTERIFICATION WITH AN UNSATURATED CARBOXYLIC ACID TOYO INK MANUFACTURING CO., LTD. (JP) 1979-12-04 US claimed
US-4177122-A ETHERIFICATION WITH AN ALKYLENE OXIDE FOLLOWED BY ESTERIFICATION WITH AN UNSATURATED CARBOXYLIC ACID TOYO INK MANUFACTURING CO., LTD. (JP) 1979-12-04 US disclosed