Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796484 | 0.80 | MEN1 (0.36) | KIF11KDM4EL3MBTL1TSHRMAPT | |
| SCHEMBL31312323 | 0.80 | KIF11 (0.35) | KIF11HSD17B10L3MBTL1MAPTATM | |
| SCHEMBL2797388 | 0.80 | L3MBTL1 (0.38) | KIF11ALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL30489827 | 0.80 | L3MBTL1 (0.38) | KIF11ALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL2799236 | 0.78 | L3MBTL1 (0.40) | KIF11KDM4EL3MBTL1RAB9AMAPK1 | |
| SCHEMBL11818712 | 0.74 | PTPN5 (0.35) | KIF11ALDH1A1PKML3MBTL1TSHR | |
| SCHEMBL439814 | 0.74 | PRKCA (0.38) | KIF11ALDH1A1KDM4EPKMHPGD | |
| SCHEMBL7139095 | 0.70 | GAA (0.43) | KIF11ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL22778035 | 0.69 | BACE1 (0.35) | KIF11ALDH1A1KDM4EPKMHPGD | |
| SCHEMBL29714441 | 0.69 | BACE1 (0.35) | KIF11ALDH1A1KDM4EPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166853-A | Antihypertensive 7-trifluoromethyl-4-aminoquinolones | THE UPJOHN COMPANY (US) | 1979-09-04 | — | — | US | disclosed |