Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 10/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | GMNN | O75496 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | APEX1 | P27695 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 4/20 | 0.38 |
| ▸ | BLM | P54132 | 4/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566523 | 0.74 | KIF11 (0.39) | MAPTALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL6752986 | 0.69 | BACE1 (0.38) | MAPTALDH1A1KDM4EKIF11ATM | |
| SCHEMBL438965 | 0.68 | PARP1 (0.39) | PRKCAMAPTALDH1A1MEN1GMNN | |
| SCHEMBL378246 | 0.66 | ALDH1A1 (0.52) | MAPTALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL31312323 | 0.65 | KIF11 (0.35) | MAPTHSD17B10KIF11ATM | |
| SCHEMBL330442 | 0.64 | ALDH1A1 (0.50) | MAPTALDH1A1MEN1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL6062984 | 0.64 | ALDH1A1 (0.50) | MAPTALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL11689624 | 0.63 | ALDH1A1 (0.48) | MAPTALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL2799236 | 0.62 | L3MBTL1 (0.40) | MAPTMEN1KMT2ANPSR1CYP3A4 | |
| SCHEMBL11818712 | 0.61 | PTPN5 (0.35) | ALDH1A1TSHRMAPK1KIF11ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |