Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | S100A4 | P26447 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HBB | P68871 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346897 | 0.67 | MEN1 (0.36) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL30665368 | 0.67 | MEN1 (0.55) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL10344203 | 0.67 | MEN1 (0.55) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL6081753 | 0.67 | MEN1 (0.55) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL692831 | 0.64 | KMT2A (0.41) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL5193117 | 0.63 | KMT2A (0.50) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL2205822 | 0.63 | S100A4 (0.56) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL3367182 | 0.62 | KMT2A (1.00) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL28144810 | 0.61 | MEN1 (0.33) | KMT2AMEN1LMNAHTR2BALDH1A1 | |
| SCHEMBL22011499 | 0.61 | GSK3B (0.46) | KMT2AMEN1POLBS100A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144258-A | ORGANIC PIGMENTS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |
| US-4065481-A | 1:1-Azomethine-metal-complex dyestuffs | CIBA-GEIGY CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-4024132-A | Azomethine pigments | CIBA-GEIGY CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-3988323-A | PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |
| US-3974149-A | TONERS | CIBA-GEIGY CORPORATION (US) | 1976-08-10 | — | — | US | disclosed |