Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CDC25B | P30305 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 2/20 | 0.35 |
| ▸ | TDP2 | O95551 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21200769 | 0.82 | MEN1 (0.36) | MEN1KMT2ACDC25BMAOALMNA | |
| SCHEMBL28144810 | 0.80 | MEN1 (0.33) | MEN1KMT2AHTR2BLMNATHRB | |
| SCHEMBL15236205 | 0.74 | IDO1 (0.36) | MEN1KMT2ACDC25BHTR2BMAOA | |
| SCHEMBL28041600 | 0.72 | HTR2B (0.33) | MEN1KMT2AHTR2BLMNATHRB | |
| SCHEMBL27741225 | 0.68 | ACHE (0.33) | MEN1KMT2ALMNATHRBBLM | |
| SCHEMBL11566679 | 0.67 | KMT2A (0.43) | MEN1KMT2AHTR2BLMNATHRB | |
| SCHEMBL3697487 | 0.67 | MEN1 (0.39) | MEN1KMT2ACDC25BMAOALMNA | |
| SCHEMBL2026326 | 0.67 | MEN1 (0.39) | MEN1KMT2ACDC25BMAOALMNA | |
| SCHEMBL31131321 | 0.67 | LMNA (0.45) | MEN1KMT2ACDC25BMAOALMNA | |
| SCHEMBL2359460 | 0.67 | IDO1 (0.44) | MEN1KMT2ACDC25BMAOALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866579-A | SELECTIVE AGONISTS FOR CLONED HUMAN ALPHA-2 ADRENERGIC RECEPTORS. | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1999-02-02 | — | — | US | disclosed |