Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3513772 | 0.80 | MEN1 (0.46) | CHRNB2CHRNA4LMNASMN1; SMN2MET | |
| SCHEMBL30454073 | 0.80 | MEN1 (0.46) | CHRNB2CHRNA4LMNASMN1; SMN2MET | |
| SCHEMBL16904329 | 0.77 | CHRNB2 (0.40) | CHRNB2CHRNA4LMNASMN1; SMN2MET | |
| SCHEMBL15689420 | 0.75 | CHRNB2 (0.36) | CHRNB2CHRNA4LMNASMN1; SMN2MET | |
| SCHEMBL20897976 | 0.75 | CHRNB2 (0.48) | CHRNB2CHRNA4LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL20897965 | 0.75 | CHRNB2 (0.48) | CHRNB2CHRNA4LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL24752408 | 0.74 | CHRNB2 (0.39) | CHRNB2CHRNA4LMNASMN1; SMN2MET | |
| SCHEMBL29189625 | 0.74 | CHRNB2 (0.39) | CHRNB2CHRNA4LMNASMN1; SMN2MET | |
| SCHEMBL30853057 | 0.74 | CHRNB2 (0.39) | CHRNB2CHRNA4LMNASMN1; SMN2MET | |
| SCHEMBL30320472 | 0.73 | LMNA (0.47) | CHRNB2CHRNA4LMNASMN1; SMN2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000485-A1 | Piperidino-propanols, their preparation and pharmaceutical compounds containing them | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |