Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11567116 | 0.81 | KMT2A (0.48) | MAPTALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL5079344 | 0.80 | CALCRL (0.44) | RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30169785 | 0.79 | MLYCD (0.46) | MAPTMEN1KMT2APDK1PDK2 | |
| SCHEMBL29221550 | 0.79 | MLYCD (0.46) | MAPTMEN1KMT2APDK1PDK2 | |
| SCHEMBL29980048 | 0.78 | PGR (0.56) | MAPTALDH1A1MEN1KMT2APDK1 | |
| SCHEMBL21626142 | 0.78 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL9222065 | 0.77 | HSD17B10 (0.59) | MAPTALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL10721870 | 0.77 | MME (0.42) | LMNARAB9ASMN1; SMN2MMEACE | |
| Bromide SCHEMBL11428373 | 0.76 | TAAR1 (0.61) | MAPTALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL9723348 | 0.75 | CASP3 (0.46) | MAPTMEN1KMT2APDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153688-A | N-TRIFLUOROACETYL-ALANYL OR LYSYL-ALANYL OR LYSYL-ANILIDE, REVERSIBLE ELASTASE ENZYME INHIBITORS | DELALANDE S.A. (FR) | 1979-05-08 | — | — | US | disclosed |