Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP9 | P55211 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14254895 | 0.79 | HDAC1 (0.56) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL7829245 | 0.75 | MAPT (0.49) | MMP2MMP3GAAPOLBPDK1 | |
| SCHEMBL11566967 | 0.75 | MAPT (0.47) | GAAPOLBPDK1PDK2PDK3 | |
| SCHEMBL10591792 | 0.74 | ALDH1A1 (0.57) | POLBHSD17B10 | |
| SCHEMBL9301420 | 0.74 | ALDH1A1 (0.57) | POLBHSD17B10 | |
| SCHEMBL27183189 | 0.74 | MLYCD (0.44) | MMP2GAAHDAC1HDAC7HDAC8 | |
| SCHEMBL23080544 | 0.73 | HTT (0.57) | GAAPOLBMEN1NPC1TP53 | |
| SCHEMBL5611391 | 0.73 | CA2 (0.47) | CASP3GAAMAPT | |
| SCHEMBL7832189 | 0.73 | CA2 (0.47) | CASP3GAAMAPT | |
| SCHEMBL473070 | 0.73 | CA2 (0.47) | CASP3GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5078129-A | Therapy for dry mouth | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1992-01-07 | — | — | US | disclosed |
| US-4839352-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1989-06-13 | — | — | US | disclosed |
| US-4820506-A | ALLEVIATING DRY MOUTH OR XEROSTOMIA; MIXTURE OF ORGANIC ACIDS, SWEETENER AND CALCIUM PHOSPHATE | RESEARCH FOUNDATION, STATE UNIVERSITY OF NEW YORK (US) | 1989-04-11 | — | — | US | disclosed |