Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565021 | 0.85 | MET (0.49) | SMN1; SMN2METBACE1 | |
| SCHEMBL11564649 | 0.84 | RORC (0.46) | SMN1; SMN2XDHMAPTTP53NPC1 | |
| SCHEMBL11565226 | 0.82 | BRAF (0.47) | SMN1; SMN2ALOX15XDHMETNPSR1 | |
| SCHEMBL11050893 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2NPSR1MAPTTP53NPC1 | |
| SCHEMBL11565436 | 0.79 | HDAC1 (0.39) | NPSR1MAPTNPC1LMNARAB9A | |
| SCHEMBL11558200 | 0.74 | CETP (0.41) | SMN1; SMN2MAPTNPC1LMNARAB9A | |
| SCHEMBL11442327 | 0.72 | RORC (0.45) | SMN1; SMN2MAPTTP53NPC1LMNA | |
| SCHEMBL11439258 | 0.72 | TDP1 (0.47) | SMN1; SMN2MAPTTP53NPC1LMNA | |
| SCHEMBL11442118 | 0.72 | KCNK3 (0.49) | SMN1; SMN2NPSR1MAPTLMNAMEN1 | |
| SCHEMBL11435252 | 0.72 | RORC (0.47) | SMN1; SMN2MAPTTP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166735-A | Cycloalkanecarboxanilide derivative herbicides | SHELL OIL COMPANY (US) | 1979-09-04 | — | — | US | disclosed |