Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 5/20 | 0.50 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.50 |
| ▸ | CLIC1 | O00299 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.45 |
| ▸ | MT-CO2 | P00403 | 4/20 | 0.44 |
| ▸ | TTR | P02766 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.44 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563738 | 0.86 | CXCL8 (0.67) | CXCL8CLCN2CLIC1CYP2C9PTGS2 | |
| SCHEMBL11563426 | 0.86 | MT-CO2 (0.56) | CXCL8CYP2C9PTGS2MT-CO2TTR | |
| SCHEMBL11561653 | 0.85 | CXCL8 (0.51) | CXCL8CLCN2CLIC1CYP2C9PTGS2 | |
| SCHEMBL11611474 | 0.84 | CXCL8 (0.50) | CXCL8CLCN2CLIC1CYP2C9PTGS2 | |
| SCHEMBL11567302 | 0.81 | CLCN2 (0.77) | CXCL8CLCN2CLIC1CYP2C9PTGS2 | |
| SCHEMBL11566076 | 0.77 | CYP2C9 (0.46) | CXCL8CLCN2CLIC1CYP2C9PTGS2 | |
| SCHEMBL11563431 | 0.76 | PTGS2 (0.76) | CXCL8CLCN2CLIC1CYP2C9PTGS2 | |
| SCHEMBL11409146 | 0.76 | PTGS2 (0.73) | CXCL8CLCN2CLIC1CYP2C9PTGS2 | |
| SCHEMBL3064448 | 0.73 | TTR (0.73) | CLCN2CYP2C9PTGS2MT-CO2TTR | |
| SCHEMBL11564340 | 0.73 | PTGS2 (0.73) | CXCL8CLCN2CLIC1CYP2C9PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092430-A | ANTICOAGULANTS, ANALGESTIC, ANTIPYRETIC ACTIVITY | CIBA-GEIGY CORPORATION (US) | 1978-05-30 | — | — | US | claimed |
| US-4173577-A | ANTICOAGULANTS; ANTIINFLAMMATORY AGENTS; ANTIPYRETICS; ANALGESICS | CIBA-GEIGY CORPORATION (US) | 1979-11-06 | — | — | US | disclosed |
| US-4092430-A | ANTICOAGULANTS, ANALGESTIC, ANTIPYRETIC ACTIVITY | CIBA-GEIGY CORPORATION (US) | 1978-05-30 | — | — | US | disclosed |