Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 8/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | TTR | P02766 | 3/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11567304 | 0.86 | CXCL8 (0.50) | MT-CO2PTGS2TTRADRA1ACYP3A4 | |
| SCHEMBL7164972 | 0.86 | CXCL8 (0.75) | MT-CO2PTGS2TTRADRA1ACYP3A4 | |
| SCHEMBL11561045 | 0.84 | P2RX7 (0.57) | MT-CO2PTGS2TTRADRA1ACYP3A4 | |
| SCHEMBL11409146 | 0.84 | PTGS2 (0.73) | MT-CO2PTGS2TTRADRA1ACYP3A4 | |
| SCHEMBL11563431 | 0.84 | PTGS2 (0.76) | MT-CO2PTGS2TTRADRA1ACYP3A4 | |
| SCHEMBL11560050 | 0.83 | PTGS2 (0.56) | MT-CO2PTGS2TTRADRA1ACYP3A4 | |
| SCHEMBL13652996 | 0.81 | MT-CO2 (0.58) | MT-CO2PTGS2TTRADRA1ACYP3A4 | |
| SCHEMBL13318494 | 0.79 | P2RX7 (0.51) | MT-CO2PTGS2TTRADRA1ACYP3A4 | |
| SCHEMBL11564340 | 0.78 | PTGS2 (0.73) | MT-CO2PTGS2TTRADRA1ACYP3A4 | |
| SCHEMBL11567302 | 0.77 | CLCN2 (0.77) | MT-CO2PTGS2TTRADRA1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4173577-A | ANTICOAGULANTS; ANTIINFLAMMATORY AGENTS; ANTIPYRETICS; ANALGESICS | CIBA-GEIGY CORPORATION (US) | 1979-11-06 | — | — | US | claimed |
| US-4092430-A | ANTICOAGULANTS, ANALGESTIC, ANTIPYRETIC ACTIVITY | CIBA-GEIGY CORPORATION (US) | 1978-05-30 | — | — | US | claimed |
| US-4173577-A | ANTICOAGULANTS; ANTIINFLAMMATORY AGENTS; ANTIPYRETICS; ANALGESICS | CIBA-GEIGY CORPORATION (US) | 1979-11-06 | — | — | US | disclosed |
| US-4092430-A | ANTICOAGULANTS, ANALGESTIC, ANTIPYRETIC ACTIVITY | CIBA-GEIGY CORPORATION (US) | 1978-05-30 | — | — | US | disclosed |