Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TYMP | P19971 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | TACR2 | P21452 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28354074 | 1.00 | GPR35 (0.41) | GPR35ALDH1A1TYMPTSHRTHRB | |
| SCHEMBL13834865 | 1.00 | GPR35 (0.41) | GPR35ALDH1A1TYMPTSHRTHRB | |
| SCHEMBL23094090 | 0.91 | NPC1 (0.33) | GPR35ALDH1A1 | |
| SCHEMBL31017017 | 0.89 | GPR35 (0.44) | GPR35ALDH1A1TYMPTSHRTHRB | |
| SCHEMBL2492202 | 0.89 | GPR35 (0.44) | GPR35ALDH1A1TYMPTSHRTHRB | |
| SCHEMBL3559696 | 0.89 | GPR35 (0.44) | GPR35ALDH1A1TYMPTSHRTHRB | |
| SCHEMBL1413157 | 0.89 | GPR35 (0.44) | GPR35ALDH1A1TYMPTSHRTHRB | |
| SCHEMBL5715261 | 0.89 | GPR35 (0.44) | GPR35ALDH1A1TYMPTSHRTHRB | |
| Bromide SCHEMBL6258898 | 0.87 | GPR35 (0.42) | GPR35ALDH1A1TYMPTSHRTHRB | |
| SCHEMBL793166 | 0.86 | GPR35 (0.40) | GPR35ALDH1A1TYMPTSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308882-B1 | Fused thiophenes and uses thereof | CORNING INC (US) | 2018-06-13 | — | — | EP | disclosed |
| EP-2773646-B1 | CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2016-06-15 | — | — | EP | disclosed |
| EP-2129678-B1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2015-05-27 | — | — | EP | disclosed |
| US-8846855-B2 | Conjugated fused thiophenes, methods of making conjugated fused thiophenes, and uses thereof | CORNING INCORPORATED (US) | 2014-09-30 | — | — | US | disclosed |
| EP-2773687-A1 | FUSED THIOPHENES, METHODS OF MAKING FUSED THIOPHENES, AND USES THEREOF | Corning Inc. (US) | 2014-09-10 | — | — | EP | disclosed |
| EP-2773646-A1 | CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF | Corning Incorporated (US) | 2014-09-10 | — | — | EP | disclosed |
| EP-1799688-B1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2013-06-19 | — | — | EP | disclosed |
| WO-2013066973-A1 | FUSED THIOPHENES, METHODS OF MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED (US) | 2013-05-10 | — | — | WO | disclosed |
| WO-2013066732-A1 | CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED (US) | 2013-05-10 | — | — | WO | disclosed |
| US-20130109821-A1 | CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED | 2013-05-02 | — | — | US | disclosed |
| US-20100010237-A1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | HE MINGQIAN | 2010-01-14 | — | — | US | disclosed |
| EP-2129678-A2 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008106019-A2 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED (US) | 2008-09-04 | — | — | WO | disclosed |
| US-20070265418-A1 | Fused Thiophenes, Methods for Making Fused Thiophenes, and Uses Thereof | CORNING INCORPORATED | 2007-11-15 | — | — | US | disclosed |
| US-20070161776-A1 | Fused thiophenes, methods for making fused thiophenes, and uses thereof | CORNING INCORPORATED | 2007-07-12 | — | — | US | disclosed |
| EP-1799688-A2 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INC. (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006031893-A2 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED (US) | 2006-03-23 | — | — | WO | disclosed |
| US-6676857-B2 | FOR USE AS SEMICONDUCTORS OR CHARGE TRANSPORT MATERIALS IN OPTICAL, ELECTROOPTICAL OR ELECTRONIC DEVICES INCLUDING FIELD EFFECT TRANSISTORS, ELECTROLUMINESCENT, PHOTOVOLTAIC AND SENSOR DEVICES | MERCK PATENT GESELLSCHAFT MIT (DE) | 2004-01-13 | — | — | US | disclosed |
| US-20030047720-A1 | Mono-, oligo- and poly-4- fluorothiophenes and their use as charge transport materials | MERCK PATENT GMBH (DE) | 2003-03-13 | — | — | US | disclosed |
| EP-1279690-A1 | Mono-oligo- and poly-3-substituted-4-fluorothiophenes and their use as charge transport materials | MERCK PATENT GmbH (DE) | 2003-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109821-A1 | CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF | TST, TPMT, TPR | GPR35 4231/4885ALDH1A1 2137/4885TYMP 27/4885 |
| US-20100010237-A1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | TPMT, TST, TYMP | GPR35 4520/4885ALDH1A1 2157/4885TYMP 3/4885 |
| US-20070265418-A1 | Fused Thiophenes, Methods for Making Fused Thiophenes, and Uses Thereof | TPMT, TST, TYMP | GPR35 4429/4885ALDH1A1 2135/4885TYMP 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.