Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5715261 | 1.00 | GPR35 (0.44) | GPR35ALDH1A1TSHRTHRBTYMP | |
| SCHEMBL31017017 | 1.00 | GPR35 (0.44) | GPR35ALDH1A1TSHRTHRBTYMP | |
| SCHEMBL2492202 | 1.00 | GPR35 (0.44) | GPR35ALDH1A1TSHRTHRBTYMP | |
| SCHEMBL1413157 | 1.00 | GPR35 (0.44) | GPR35ALDH1A1TSHRTHRBTYMP | |
| Bromide SCHEMBL6258898 | 0.98 | GPR35 (0.42) | GPR35ALDH1A1TSHRTHRBTYMP | |
| SCHEMBL4824479 | 0.90 | HTT (0.37) | GPR35ALDH1A1TSHRTYMPKDM4E | |
| SCHEMBL13834865 | 0.89 | GPR35 (0.41) | GPR35ALDH1A1TSHRTHRBTYMP | |
| SCHEMBL28354074 | 0.89 | GPR35 (0.41) | GPR35ALDH1A1TSHRTHRBTYMP | |
| SCHEMBL12440886 | 0.89 | GPR35 (0.41) | GPR35ALDH1A1TSHRTHRBTYMP | |
| SCHEMBL1156732 | 0.89 | GPR35 (0.41) | GPR35ALDH1A1TSHRTHRBTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1956988-B | Mono-, oligo-and polythieno [3,2-b ] thiophenes | MERCK PATENT GMBH | 2014-03-26 | — | — | CN | disclosed |
| US-7714098-B2 | Mono-, oligo- and polythieno[3,2-b]thiophenes | MERCK PATENT GMBH (DE) | 2010-05-11 | — | — | US | disclosed |
| US-7714098-B2 | Mono-, oligo- and polythieno[3,2-b]thiophenes | MERCK PATENT GMBH (DE) | 2010-05-11 | — | — | US | disclosed |
| EP-1751166-B1 | MONO-, OLIGO- AND POLYTHIENO[3,2-B]THIOPHENES | MERCK PATENT GMBH (DE) | 2009-10-28 | — | — | EP | disclosed |
| US-7470377-B2 | Monomers, oligomers and polymers comprising thiophene and selenophene | MERCK PATENT GMBH (DE) | 2008-12-30 | — | — | US | disclosed |
| US-7470377-B2 | Monomers, oligomers and polymers comprising thiophene and selenophene | MERCK PATENT GMBH (DE) | 2008-12-30 | — | — | US | disclosed |
| US-20080303000-A1 | Monomers, Oligomers and Polymers Comprising Thiophene and Selenophene | MERCK PATENT GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
| US-20080303000-A1 | Monomers, Oligomers and Polymers Comprising Thiophene and Selenophene | MERCK PATENT GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
| US-7462726-B2 | Conjugated thiophene compound comprising perfluorinated and alkylated sidechains, conductive organic thin film containing the compound, and field-effect type organic transistor employing the thin film | CANON KABUSHIKI KAISHA (JP) | 2008-12-09 | — | — | US | disclosed |
| EP-1856178-A1 | MONOMERS, OLIGOMERS AND POLYMERS COMPRISING THIOPHENE AND SELENOPHENE | Merck Patent GmbH (DE) | 2007-11-21 | — | — | EP | disclosed |
| US-20070232812-A1 | Mono-, Oligo- and Polythieno [3,2-B]Thiophenes | MERCK PATENT GMBH (DE) | 2007-10-04 | — | — | US | disclosed |
| US-20070232812-A1 | Mono-, Oligo- and Polythieno [3,2-B]Thiophenes | MERCK PATENT GMBH (DE) | 2007-10-04 | — | — | US | disclosed |
| EP-1751166-A1 | MONO-, OLIGO- AND POLYTHIENO[3,2-B]THIOPHENES | MERCK PATENT GmbH (DE) | 2007-02-14 | — | — | EP | disclosed |
| US-20060249712-A1 | Monomers, oligomers and polymers comprising thiophene and selenophene | MERCK PATENT GMBH (DE) | 2006-11-09 | — | — | US | disclosed |
| US-20060234335-A1 | Conjugated thiophene compound, conprising perfluorinated and alkylated sidechains, conductive organic thin film containing the compound, and field-effect type organic transistor employing the thin film | CANON KABUSHIKI KAISHA (JP) | 2006-10-19 | — | — | US | disclosed |
| WO-2006094645-A1 | MONOMERS, OLIGOMERS AND POLYMERS COMPRISING THIOPHENE AND SELENOPHENE | MERCK PATENT GMBH (DE) | 2006-09-14 | — | — | WO | disclosed |
| WO-2005111045-A1 | MONO-, OLIGO- AND POLYTHIENO[3,2-b]THIOPHENES | MERCK PATENT GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |
| WO-2005070992-A2 | CONJUGATED THIOPHENE COMPOUND, CONPRISING PERFLUORINATED AND ALKYLATED SIDECHAINS, CONDUCTIVE ORGANIC THIN FILM CONTAINING THE COMPOUND, AND FIELD-EFFECT TYPE ORGANIC TRANSISTOR EMPLOYING THE THIN FILM | CANON KABUSHIKI KAISHA (JP) | 2005-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232812-A1 | Mono-, Oligo- and Polythieno [3,2-B]Thiophenes | FHIT, FUBP3, SLCO1B3 | GPR35 3415/4885ALDH1A1 3925/4885TSHR 1273/4885 |
| US-20080303000-A1 | Monomers, Oligomers and Polymers Comprising Thiophene and Selenophene | SELENOI, SELE, SLCO2A1 | GPR35 2607/4885ALDH1A1 3422/4885TSHR 3659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.