Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564699 | 0.87 | DRD2 (0.39) | DRD2OPRD1LMNABCL2L1BAD | |
| SCHEMBL29963667 | 0.81 | DRD2 (0.38) | DRD2OPRD1LMNAOPRM1 | |
| SCHEMBL8122525 | 0.80 | HTR1A (0.38) | HTR1ALMNAALDH1A1KDM4E | |
| SCHEMBL12111122 | 0.80 | HTR1A (0.38) | HTR1ALMNAALDH1A1KDM4E | |
| SCHEMBL15485106 | 0.79 | LMNA (0.51) | LMNAALDH1A1KDM4E | |
| SCHEMBL29963948 | 0.79 | LMNA (0.51) | LMNAALDH1A1KDM4E | |
| SCHEMBL743626 | 0.79 | LMNA (0.51) | LMNAALDH1A1KDM4E | |
| SCHEMBL10814290 | 0.72 | DRD2 (0.37) | DRD2OPRD1OPRM1 | |
| SCHEMBL19954245 | 0.70 | POLB (0.33) | HTR1ALMNAAKT1 | |
| SCHEMBL8469239 | 0.70 | POLB (0.33) | HTR1ALMNAAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001486-A2 | Process for preparing 2,3-dihydro-2,2-dimethyl-7-benzofuranol and benzodioxole intermediate therefor | FMC Corporation (US) | 1979-04-18 | — | — | EP | disclosed |
| US-4118400-A | THERMAL REARRANGEMENT OF 2-ISOPROPYL-1.3-BENZODIOXOLE, ACID CATALYST | FMC CORPORATION (US) | 1978-10-03 | — | — | US | disclosed |