Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.55 |
| ▸ | CTSB | P07858 | 5/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569751 | 0.90 | MMP1 (0.51) | CTSKCTSBMMP1MMP9MMP8 | |
| SCHEMBL11567621 | 0.88 | CTSK (0.55) | CTSKCTSBCTSSCTSL | |
| SCHEMBL11567622 | 0.88 | CTSK (0.55) | CTSKCTSBCTSSCTSL | |
| SCHEMBL11567669 | 0.87 | CTSK (0.53) | CTSKCTSB | |
| Hydrochloric Acid SCHEMBL11568557 | 0.87 | CTSK (0.54) | CTSKCTSBCTSSCTSL | |
| Hydrochloric Acid SCHEMBL11568559 | 0.87 | CTSK (0.54) | CTSKCTSBCTSSCTSL | |
| SCHEMBL18775048 | 0.82 | CTSK (0.60) | CTSKCTSBCTSSCTSL | |
| SCHEMBL25634730 | 0.82 | CTSK (0.60) | CTSKCTSBCTSSCTSL | |
| SCHEMBL11764262 | 0.80 | CTSK (0.58) | CTSKCTSBCTSSCTSL | |
| SCHEMBL11764270 | 0.80 | CTSK (0.58) | CTSKCTSBCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | disclosed |