Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564788 | 0.90 | PKM (0.62) | PKMAOC3NPSR1KDM4EHCAR3 | |
| SCHEMBL11564881 | 0.82 | HCAR3 (0.66) | PKMAOC3HCAR3 | |
| SCHEMBL11564050 | 0.82 | LMNA (0.43) | NPSR1KDM4EHCAR3CCR1CCR5 | |
| SCHEMBL11566621 | 0.81 | PKM (0.52) | PKMKCNH2AOC3HCAR3TAAR1 | |
| SCHEMBL13103012 | 0.80 | HRH3 (0.47) | PKMAOC3HCAR3POLBHRH3 | |
| SCHEMBL11561492 | 0.80 | PKM (0.51) | PKMKCNH2AOC3 | |
| SCHEMBL9906944 | 0.79 | POLB (0.51) | PKMAOC3HCAR3POLBCCR1 | |
| SCHEMBL14554344 | 0.79 | HCAR3 (0.41) | PKMAOC3HCAR3POLBTAAR1 | |
| SCHEMBL11563043 | 0.79 | SIGMAR1 (0.53) | PKMKCNH2AOC3HDAC6 | |
| SCHEMBL19074154 | 0.77 | HCAR3 (0.41) | PKMAOC3NPSR1KDM4EHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000816-A1 | Substituted amino-pyridine derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1979-02-21 | — | — | EP | disclosed |