SCHEMBL2277437

SCHEMBL2277437

CC(C)C1=C(C(C)C)N(c2ccccc2)CC=N1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
POLB P06746 1/20 0.31
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
BRD4 O60885 1/20 0.30
BRD2 P25440 1/20 0.30
BRD3 Q15059 1/20 0.30
LMNA P02545 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11568355 0.67 MAPT (0.40) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL11748730 0.67 MEN1 (0.48) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL12821098 0.65 SIGMAR1 (0.40) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL11267203 0.63 MAPT (0.38) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL28975392 0.63 SIGMAR1 (0.39) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL28485542 0.63 SIGMAR1 (0.39) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL30309571 0.63 SIGMAR1 (0.39) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL9668729 0.62 SIGMAR1 (0.64) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL28851962 0.60 SIGMAR1 (0.56) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL4989931 0.56 NPC1 (0.37) SIGMAR1MEN1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3161834-A1 SATURATED-DIMER-ACID-DIESTER DIELECTRIC FLUID Dow Global Technologies Llc (US) 2017-05-03 EP disclosed
EP-2723840-A1 GENETICALLY-ENGINEERED MICROBIAL OIL DIELECTRIC FLUID Dow Global Technologies LLC (US) 2014-04-30 EP disclosed
WO-2013003268-A1 GENETICALLY-ENGINEERED MICROBIAL OIL DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2013-01-03 WO disclosed
EP-2519589-A1 ALGAE OIL BASED DIELECTRIC FLUID FOR ELECTRICAL COMPONENTS Dow Global Technologies LLC (US) 2012-11-07 EP disclosed
WO-2011090685-A1 ALGAE OIL BASED DIELECTRIC FLUID FOR ELECTRICAL COMPONENTS DOW GLOBAL TECHNOLOGIES LLC (US) 2011-07-28 WO disclosed