Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG2 | P78540 | 2/20 | 0.52 |
| ▸ | ARG1 | P05089 | 1/20 | 0.52 |
| ▸ | NOS2 | P35228 | 3/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BHMT | Q93088 | 3/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358490 | 0.90 | ARG2 (0.47) | ARG2ARG1NOS2NOS1NOS3 | |
| SCHEMBL11564550 | 0.90 | ARG2 (0.47) | ARG2ARG1NOS2NOS1NOS3 | |
| SCHEMBL8081083 | 0.88 | ARG2 (0.46) | ARG2ARG1NOS2NOS1NOS3 | |
| SCHEMBL15795239 | 0.84 | ARG1 (0.50) | ARG2ARG1NOS2NOS1NOS3 | |
| SCHEMBL15795237 | 0.84 | ARG1 (0.50) | ARG2ARG1NOS2NOS1NOS3 | |
| SCHEMBL29393779 | 0.83 | ARG1 (0.61) | ARG2ARG1NOS2NOS1NOS3 | |
| SCHEMBL36933 | 0.83 | ARG1 (0.61) | ARG2ARG1NOS2NOS1NOS3 | |
| SCHEMBL36935 | 0.83 | ARG1 (0.61) | ARG2ARG1NOS2NOS1NOS3 | |
| SCHEMBL36934 | 0.83 | ARG1 (0.61) | ARG2ARG1NOS2NOS1NOS3 | |
| SCHEMBL29378137 | 0.83 | ARG1 (0.61) | ARG2ARG1NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139635-A | Cysteamine derivatives for oral treatment of seborrhea | L'OREAL (FR) | 1979-02-13 | — | — | US | disclosed |
| US-4035492-A | Oral treatment of seborrhea with cysteamine derivatives | L'OREAL (FR) | 1977-07-12 | — | — | US | disclosed |
| US-3950542-A | Cysteamine derivatives for oral treatment of seborrhea | L'OREAL (FR) | 1976-04-13 | — | — | US | disclosed |