SCHEMBL8081083

SCHEMBL8081083

N[C@@H](CSCC=CC(=O)O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ARG2 P78540 2/20 0.46
▸ ARG1 P05089 1/20 0.46
▸ NOS2 P35228 3/20 0.41
▸ NOS1 P29475 2/20 0.41
▸ NOS3 P29474 1/20 0.41
▸ GABRR1 P24046 2/20 0.40
▸ GABRR2 P28476 2/20 0.40
▸ BLM P54132 2/20 0.40
▸ GABRR3 A8MPY1 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ APEX1 P27695 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ BHMT Q93088 3/20 0.37
▸ BHMT2 Q9H2M3 1/20 0.37
▸ PTGS1 P23219 1/20 0.35
▸ SLC7A11 Q9UPY5 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11568907 0.88 ARG2 (0.52) ARG2ARG1NOS2NOS1NOS3
SCHEMBL358490 0.82 ARG2 (0.47) ARG2ARG1NOS2NOS1NOS3
SCHEMBL11564550 0.82 ARG2 (0.47) ARG2ARG1NOS2NOS1NOS3
SCHEMBL15795239 0.78 ARG1 (0.50) ARG2ARG1NOS2NOS1NOS3
SCHEMBL15795237 0.78 ARG1 (0.50) ARG2ARG1NOS2NOS1NOS3
SCHEMBL7856299 0.76 TSHR (0.50) GABRR1GABRR2BLMGABRR3LMNA
SCHEMBL36934 0.76 ARG1 (0.61) ARG2ARG1NOS2NOS1NOS3
SCHEMBL36933 0.76 ARG1 (0.61) ARG2ARG1NOS2NOS1NOS3
SCHEMBL36935 0.76 ARG1 (0.61) ARG2ARG1NOS2NOS1NOS3
SCHEMBL29393779 0.76 ARG1 (0.61) ARG2ARG1NOS2NOS1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0563865-B1 Method and apparatus for analyzing hemoglobins and solution for suppressing column deterioration for use therein HITACHI LTD (JP) 2000-09-13 — — EP claimed
EP-0588335-B1 Separation column and method for preventing its deterioration HITACHI LTD (JP) 1997-02-05 — — EP claimed
US-5468379-A S-/Carboxyalkyl/-L-cysteine deterioration suppressor and surfactant for solubilizing contaminants originating from blood samples HITACHI, LTD. (JP) 1995-11-21 — — US claimed
US-5407568-A Separation column containing S-carboxyalkylcysteine HITACHI, LTD. (JP) 1995-04-18 — — US claimed
US-5358639-A Liquid chromatography; packed with filler containing S-(caroxyalkyl)-L-cysteine, phosphate buffer solution and surfactant HITACHI, LTD. (JP) 1994-10-25 — — US claimed
EP-0588335-A1 Separation column and method for preventing its deterioration HITACHI, LTD. (JP) 1994-03-23 — — EP claimed
EP-0563865-A2 Method and apparatus for analyzing hemoglobins and solution for suppressing column deterioration for use therein HITACHI, LTD. (JP) 1993-10-06 — — EP claimed
JP-5281222-A — — None — — JP disclosed
JP-6094695-A — — None — — JP disclosed
EP-2960648-B1 MEASUREMENT METHOD, MEASUREMENT APPARATUS, AND ELUENT FOR THE ANALYSIS OF HEMOGLOBINS ARKRAY INC (JP) 2017-03-29 — — EP disclosed
US-20150377846-A1 MEASUREMENT METHOD, MEASUREMENT APPARATUS, AND ELUENT ARKRAY INC (JP) 2015-12-31 — — US disclosed
EP-2960648-A1 MEASUREMENT METHOD, MEASUREMENT APPARATUS, AND ELUENT FOR THE ANALYSIS OF HEMOGLOBINS ARKRAY, Inc. (JP) 2015-12-30 — — EP disclosed
EP-0563865-B1 Method and apparatus for analyzing hemoglobins and solution for suppressing column deterioration for use therein HITACHI LTD (JP) 2000-09-13 — — EP disclosed
US-5358639-A Liquid chromatography; packed with filler containing S-(caroxyalkyl)-L-cysteine, phosphate buffer solution and surfactant HITACHI, LTD. (JP) 1994-10-25 — — US disclosed
US-5358639-A Liquid chromatography; packed with filler containing S-(caroxyalkyl)-L-cysteine, phosphate buffer solution and surfactant HITACHI, LTD. (JP) 1994-10-25 — — US disclosed
JP-H0694695-A SEPARATION COLUMN, PREVENTION OF DETERIORATION OF SEPARATION COLUMN, TRANSPORT AND HANDLING OF SEPARATION COLUMN AND SEALING SOLUTION FOR SEPARATION COLUMN HITACHI LTD 1994-04-08 — — JP disclosed
EP-0588335-A1 Separation column and method for preventing its deterioration HITACHI, LTD. (JP) 1994-03-23 — — EP disclosed
JP-H05281222-A METHOD AND APPARATUS FOR ANALYSIS OF HEMOGLOBIN AND COLUMN DETERIORATION-SUPPRESSING LIQUID USED FOR THEM HITACHI LTD 1993-10-29 — — JP disclosed
EP-0563865-A2 Method and apparatus for analyzing hemoglobins and solution for suppressing column deterioration for use therein HITACHI, LTD. (JP) 1993-10-06 — — EP disclosed
EP-0563865-A2 Method and apparatus for analyzing hemoglobins and solution for suppressing column deterioration for use therein HITACHI, LTD. (JP) 1993-10-06 — — EP disclosed
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