Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | BAX | Q07812 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11193479 | 0.83 | TLR4 (0.47) | LTA4HTSHRMAOATLR4TLR2 | |
| SCHEMBL87669 | 0.80 | ALDH1A1 (0.52) | TSHRSMN1; SMN2MAOAALDH1A1MEN1 | |
| SCHEMBL354205 | 0.79 | ALDH1A1 (0.59) | LTA4HTSHRRAB9ASMN1; SMN2NR1H2 | |
| SCHEMBL1251481 | 0.78 | LTA4H (0.55) | LTA4HTSHRRAB9ASMN1; SMN2NR1H2 | |
| SCHEMBL28054773 | 0.77 | ALDH1A1 (0.41) | TSHRGAAHTTALDH1A1HPGD | |
| SCHEMBL8709613 | 0.76 | LTA4H (0.48) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL4532036 | 0.75 | ALDH1A1 (0.56) | TSHRRAB9ASMN1; SMN2ALDH1A1HPGD | |
| Diphenylether SCHEMBL28042732 | 0.74 | LTA4H (0.46) | LTA4HTSHRGAARAB9AGLA | |
| SCHEMBL7704998 | 0.74 | LTA4H (0.46) | LTA4HTSHRRAB9ANR1H2BAX | |
| Diphenylether SCHEMBL27718703 | 0.74 | LTA4H (0.57) | LTA4HTSHRGAARAB9AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175138-A | α-Alkyl-p-phenoxy benzyl alcohols, compositions and treating lipidemia | SANDOZ, INC. (US) | 1979-11-20 | — | — | US | disclosed |
| US-4085149-A | HYPOLIPIDEMIC | SANDOZ, INC. (US) | 1978-04-18 | — | — | US | disclosed |