Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1004990 | 0.79 | ALDH1A1 (0.62) | ALDH1A1CYP2A6CYP3A4TP53TSHR | |
| SCHEMBL6194298 | 0.79 | NQO1 (0.56) | ALDH1A1TP53TSHRSMN1; SMN2RELA | |
| SCHEMBL7711464 | 0.77 | ALDH1A1 (0.54) | ALDH1A1CYP2A6CYP3A4TP53TSHR | |
| SCHEMBL28436 | 0.77 | ALDH1A1 (0.58) | ALDH1A1CYP2A6CYP3A4TP53TSHR | |
| SCHEMBL678625 | 0.77 | ALDH1A1 (0.58) | ALDH1A1CYP2A6CYP3A4TP53TSHR | |
| SCHEMBL6159256 | 0.76 | CHRM5 (0.55) | CYP3A4RELACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL3184498 | 0.76 | ALDH1A1 (0.58) | ALDH1A1CYP2A6CYP3A4TP53TSHR | |
| SCHEMBL1253022 | 0.76 | ALDH1A1 (0.58) | ALDH1A1CYP2A6CYP3A4TP53TSHR | |
| SCHEMBL3350071 | 0.76 | ALDH1A1 (0.58) | ALDH1A1CYP2A6CYP3A4TP53TSHR | |
| SCHEMBL11568942 | 0.75 | LTA4H (0.48) | ALDH1A1TSHRSMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9526699-B2 | Biodegradable and thermosensitive poly(organophosphazene) hydrogel, preparation method thereof and use thereof | KIST (KR) | 2016-12-27 | — | — | US | disclosed |
| US-8287888-B2 | Thermosensitive polyphosphazene-bioactive molecule conjugates, preparation method thereof and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-10-16 | — | — | US | disclosed |
| US-20090181088-A1 | THERMOSENSITIVE POLYPHOSPHAZENE-BIOACTIVE MOLECULE CONJUGATES, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-07-16 | — | — | US | disclosed |
| US-20090022683-A1 | Biodegradable and Thermosensitive Poly(Organophosphazene) Hydrogel, Preparation Method Thereof and Use Thereof | KIST (KR) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090022683-A1 | Biodegradable and Thermosensitive Poly(Organophosphazene) Hydrogel, Preparation Method Thereof and Use Thereof | PHOSPHO1, PGLS, LIPE | ALDH1A1 3589/4885CYP2A6 2431/4885CYP3A4 1176/4885 |
| US-20090181088-A1 | THERMOSENSITIVE POLYPHOSPHAZENE-BIOACTIVE MOLECULE CONJUGATES, PREPARATION METHOD THEREOF AND USE THEREOF | PHOSPHO1, PLK1, PLA2G2C | ALDH1A1 3103/4885CYP2A6 1881/4885CYP3A4 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.