Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634714 | 0.93 | ALDH1A1 (0.43) | LMNAMAPK1SMN1; SMN2CDK1CCNB1 | |
| SCHEMBL16415763 | 0.90 | LMNA (0.39) | LMNAMAPK1SMN1; SMN2CDK1CCNB1 | |
| SCHEMBL19695054 | 0.87 | MAPK1 (0.39) | LMNAMAPK1SMN1; SMN2CDK1CCNB1 | |
| SCHEMBL18830659 | 0.87 | MAPK1 (0.39) | LMNAMAPK1SMN1; SMN2CDK1CCNB1 | |
| SCHEMBL28357278 | 0.87 | LMNA (0.47) | LMNAMAPK1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24383314 | 0.86 | LMNA (0.54) | LMNAMAPK1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11322790 | 0.86 | NAAA (0.45) | ALDH1A1TDP1USP2ALOX15 | |
| SCHEMBL19707938 | 0.86 | KDM4E (0.40) | LMNAMAPK1SMN1; SMN2CDK1CCNB1 | |
| SCHEMBL17616839 | 0.85 | MAPK1 (0.42) | LMNAMAPK1SMN1; SMN2CDK1CCNB1 | |
| SCHEMBL17601883 | 0.85 | MAPK1 (0.42) | LMNAMAPK1SMN1; SMN2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150237-A | INTERMEDIATES IN THE FORMATION OF EPOXIDES | THE DOW CHEMICAL COMPANY (US) | 1979-04-17 | — | — | US | claimed |