SCHEMBL8634714

SCHEMBL8634714

O=C(CCCCC(=O)OCC1CC=CCC1)OCC1CC=CCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
TDP1 Q9NUW8 3/20 0.43
USP2 O75604 1/20 0.43
ALOX15 P16050 1/20 0.43
MAPK1 P28482 1/20 0.41
LMNA P02545 2/20 0.41
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.36
CDK1 P06493 1/20 0.35
CCNB1 P14635 1/20 0.35
CCNA2 P20248 1/20 0.35
CDK2 P24941 1/20 0.35
CCNA1 P78396 1/20 0.35
KDM4E B2RXH2 3/20 0.35
PKM P14618 1/20 0.35
LPAR1 Q92633 2/20 0.34
LPAR3 Q9UBY5 2/20 0.34
SCN9A Q15858 1/20 0.34
NLRP3 Q96P20 1/20 0.33
MAOA P21397 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28357278 0.94 LMNA (0.47) ALDH1A1TDP1USP2ALOX15MAPK1
SCHEMBL11568985 0.93 LMNA (0.47) ALDH1A1TDP1USP2ALOX15MAPK1
SCHEMBL11322790 0.92 NAAA (0.45) ALDH1A1TDP1USP2ALOX15LPAR1
SCHEMBL24383314 0.92 LMNA (0.54) ALDH1A1TDP1USP2ALOX15MAPK1
SCHEMBL16415763 0.87 LMNA (0.39) ALDH1A1TDP1USP2ALOX15MAPK1
SCHEMBL17616825 0.85 ALDH1A1 (0.37) ALDH1A1TDP1USP2ALOX15MAPK1
SCHEMBL19695054 0.84 MAPK1 (0.39) ALDH1A1TDP1MAPK1LMNAPOLB
SCHEMBL18830659 0.84 MAPK1 (0.39) ALDH1A1TDP1MAPK1LMNAPOLB
SCHEMBL19707938 0.83 KDM4E (0.40) ALDH1A1TDP1USP2ALOX15MAPK1
SCHEMBL17616839 0.82 MAPK1 (0.42) ALDH1A1TDP1MAPK1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109912544-B Method for preparing bis ((3, 4-epoxycyclohexyl) methyl) adipate by using microchannel reactor 江苏泰特尔新材料科技股份有限公司 2022-04-01 CN claimed
US-20230212133-A1 Safe, Environmentally Friendly and Controllable Method for Preparing Cycloaliphatic Diepoxides JIANGSU TETRA NEW MATERIAL TECHNOLOGY CO., LTD. (CN) 2023-07-06 US disclosed
US-20230212133-A1 Safe, Environmentally Friendly and Controllable Method for Preparing Cycloaliphatic Diepoxides JIANGSU TETRA NEW MATERIAL TECHNOLOGY CO., LTD. (CN) 2023-07-06 US disclosed
EP-3992186-A1 SAFE, ENVIRONMENTALLY FRIENDLY AND CONTROLLABLE PROCESS FOR SYNTHESIZING DIEPOXIDE Jiangsu Tetra New Material Technology Co., Ltd. (CN) 2022-05-04 EP disclosed
CN-109912544-B Method for preparing bis ((3, 4-epoxycyclohexyl) methyl) adipate by using microchannel reactor 江苏泰特尔新材料科技股份有限公司 2022-04-01 CN disclosed
CN-109912544-B Method for preparing bis ((3, 4-epoxycyclohexyl) methyl) adipate by using microchannel reactor 江苏泰特尔新材料科技股份有限公司 2022-04-01 CN disclosed
US-9499505-B2 Process for the epoxidation of olefins CHANG CHUN PLASTICS CO., LTD. (TW) 2016-11-22 US disclosed
US-9499505-B2 Process for the epoxidation of olefins CHANG CHUN PLASTICS CO., LTD. (TW) 2016-11-22 US disclosed
US-20160177023-A1 CONTINUOUS PROCESS OF OLEFINIC EPOXIDATION BY SUPPORTED HETEROPOLY ACID CHANG CHUN PLASTICS CO., LTD. (TW) 2016-06-23 US disclosed
US-20160177023-A1 CONTINUOUS PROCESS OF OLEFINIC EPOXIDATION BY SUPPORTED HETEROPOLY ACID CHANG CHUN PLASTICS CO., LTD. (TW) 2016-06-23 US disclosed
EP-0514994-B1 Liquid compositions based on polyisocyanates and epoxides ENICHEM SPA (IT) 1995-09-06 EP disclosed
EP-0655472-A1 Microwave-polymerizable isocyanate/epoxy resins for heavy-duty applications ENIRICERCHE S.p.A. (IT) 1995-05-31 EP disclosed
US-5326833-A Liquid reactive compositions comprising polyisocyanates, epoxides and solutions of alkali metal halides in polyoxyalkylenic compounds ENICHEM S.P.A. (IT) 1994-07-05 US disclosed
EP-0598433-A2 Process for curing polymerizable liquid compositions based on polyisocyanates and epoxides ENICHEM S.p.A. (IT) 1994-05-25 EP disclosed
US-5314983-A Process for curing polymerizable liquid compositions based on polyisocyanates and epoxides ENICHEM S.P.A. (IT) 1994-05-24 US disclosed
US-5288833-A Thermosetting resin with high softening point ISTITUTO GUIDO DONEGANI S.P.A. (IT) 1994-02-22 US disclosed
EP-0546602-A1 Liquid reactive compositions comprising polyisocyanates, epoxides and solutions of alkali metal halides in polyoxyalkylenic compounds ENICHEM S.p.A. (IT) 1993-06-16 EP disclosed
EP-0514994-A1 Liquid compositions based on polyisocyanates and epoxides ENICHEM S.p.A. (IT) 1992-11-25 EP disclosed
US-5145880-A LIQUID, REACTIVE COMPOSITIONS ENDOWED WITH HIGH POLYMERIZATION SPEED, CONTAINING POLYISOCYANATES AND COMPOUNDS WITH ONE OR MORE EPOXY GROUPS ENICHEM S.P.A. (IT) 1992-09-08 US disclosed
EP-0454207-A1 Liquid, reactive compositions endowed with high polymerization speed, containing polyisocyanates and compounds with one or more epoxy groups ENICHEM S.p.A. (IT) 1991-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212133-A1 Safe, Environmentally Friendly and Controllable Method for Preparing Cycloaliphatic Diepoxides DDT, EPHX2, HSD11B2 ALDH1A1 466/4885TDP1 623/4885USP2 729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.