Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496394 | 1.00 | TSHR (0.41) | TSHRPOLBCYP3A4PARP1MAPT | |
| SCHEMBL2640929 | 0.80 | ALOX5 (0.52) | TSHRPOLBCYP3A4PARP1MAPT | |
| SCHEMBL10576787 | 0.78 | ALDH1A1 (0.47) | TSHRPOLBCYP3A4PARP1MAPT | |
| SCHEMBL27274107 | 0.78 | ALDH1A1 (0.47) | TSHRPOLBCYP3A4PARP1MAPT | |
| SCHEMBL4202113 | 0.78 | ALDH1A1 (0.59) | TSHRPOLBCYP3A4PARP1MAPT | |
| SCHEMBL28095961 | 0.78 | ALDH1A1 (0.46) | TSHRPOLBCYP3A4PARP1MAPT | |
| SCHEMBL7560686 | 0.77 | ALOX5 (0.44) | TSHRPOLBCYP3A4PARP1MAPT | |
| Hydrochloric Acid SCHEMBL27955872 | 0.76 | ALDH1A1 (0.44) | TSHRPOLBCYP3A4PARP1MAPT | |
| SCHEMBL26624954 | 0.76 | AKT1 (0.42) | CYP2C19LMNAALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL3276914 | 0.76 | ALDH1A1 (0.41) | TSHRPOLBCYP3A4PARP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103981228-A | Method for preparing N-carbamoyl hydroxyphenylglycine through catalyzing phenyl hydantoin by lipase | UNIV ZHEJIANG TECHNOLOGY | 2014-08-13 | — | — | CN | disclosed |
| CN-103981228-A | Method for preparing N-carbamoyl hydroxyphenylglycine through catalyzing phenyl hydantoin by lipase | UNIV ZHEJIANG TECHNOLOGY | 2014-08-13 | — | — | CN | disclosed |
| EP-0001319-A1 | Process for the preparation of hydroxyphenyl hydantoin and of hydroxyphenyl glycine, and compounds thus obtained | BEECHAM GROUP PLC (GB) | 1979-04-04 | — | — | EP | disclosed |