Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11561098 | 0.76 | ALDH1A1 (0.43) | KMT2ARAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL11527377 | 0.76 | MEN1 (0.41) | MEN1KMT2AL3MBTL1RAB9ADRD2 | |
| SCHEMBL20159374 | 0.74 | SMN1; SMN2 (0.39) | MEN1KMT2AL3MBTL1RAB9ALMNA | |
| SCHEMBL20159516 | 0.74 | PDE4B (0.34) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL20142913 | 0.70 | SMN1; SMN2 (0.39) | MEN1KMT2AL3MBTL1RAB9ALMNA | |
| SCHEMBL20138839 | 0.70 | CYP19A1 (0.39) | MEN1KMT2AL3MBTL1RAB9ALMNA | |
| SCHEMBL11529915 | 0.69 | PDE4D (0.43) | — | |
| SCHEMBL11568698 | 0.69 | MAOB (0.40) | RAB9AMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11529917 | 0.69 | PDE4D (0.43) | — | |
| SCHEMBL11529928 | 0.69 | PDE4D (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931176-A | CNS DEPRESSANT | SANDOZ INC. (US) | 1976-01-06 | — | — | US | claimed |
| US-4136184-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS | SANDOZ, INC. (US) | 1979-01-23 | — | — | US | disclosed |
| US-4055644-A | CNS DEPRESSANTS | SANDOZ, INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3931176-A | CNS DEPRESSANT | SANDOZ INC. (US) | 1976-01-06 | — | — | US | disclosed |