Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 20/20 | 0.43 |
| ▸ | PDE4A | P27815 | 19/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 19/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529928 | 1.00 | PDE4D (0.43) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11746013 | 1.00 | PDE4D (0.43) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11529915 | 1.00 | PDE4D (0.43) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11568698 | 0.79 | MAOB (0.40) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11561098 | 0.76 | ALDH1A1 (0.43) | — | |
| SCHEMBL11531244 | 0.71 | MAOB (0.41) | — | |
| SCHEMBL11569239 | 0.69 | MEN1 (0.45) | — | |
| SCHEMBL11562685 | 0.68 | MEN1 (0.39) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11555166 | 0.65 | ACHE (0.38) | — | |
| SCHEMBL11561396 | 0.65 | NT5E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136184-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS | SANDOZ, INC. (US) | 1979-01-23 | — | — | US | disclosed |