Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 5/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11567448 | 0.90 | CTSK (0.55) | MMP1CTSKCTSBMMP9MMP8 | |
| SCHEMBL11568405 | 0.83 | MME (0.50) | MMP1CTSKCTSBCTSD | |
| SCHEMBL11568394 | 0.83 | MME (0.50) | MMP1CTSKCTSBCTSD | |
| SCHEMBL11567621 | 0.81 | CTSK (0.55) | CTSKCTSBCTSD | |
| SCHEMBL11567622 | 0.81 | CTSK (0.55) | CTSKCTSBCTSD | |
| Hydrochloric Acid SCHEMBL11568559 | 0.80 | CTSK (0.54) | CTSKCTSBCTSD | |
| Hydrochloric Acid SCHEMBL11568557 | 0.80 | CTSK (0.54) | CTSKCTSBCTSD | |
| SCHEMBL11568495 | 0.79 | BACE1 (0.52) | BACE1BACE2 | |
| SCHEMBL11569823 | 0.79 | BACE1 (0.52) | BACE1BACE2 | |
| SCHEMBL11568958 | 0.78 | LTA4H (0.52) | BACE1ERAP2ERAP1LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | disclosed |