Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1062711 | 0.73 | TDP1 (0.56) | ALDH1A1POLBTDP1MEN1KMT2A | |
| SCHEMBL5076356 | 0.73 | TDP1 (0.56) | ALDH1A1POLBTDP1MEN1KMT2A | |
| SCHEMBL20346213 | 0.72 | TDP1 (0.45) | ALDH1A1POLBTDP1MEN1KMT2A | |
| SCHEMBL8725980 | 0.71 | TDP1 (0.52) | ALDH1A1POLBTDP1MEN1KMT2A | |
| SCHEMBL10949610 | 0.71 | TDP1 (0.45) | ALDH1A1POLBTDP1MEN1KMT2A | |
| SCHEMBL8731646 | 0.68 | TDP1 (0.42) | ALDH1A1POLBTDP1MEN1KMT2A | |
| SCHEMBL3457059 | 0.68 | ALDH1A1 (0.58) | ALDH1A1POLBTDP1KMT2ALMNA | |
| SCHEMBL11573958 | 0.68 | ALDH1A1 (0.58) | ALDH1A1POLBTDP1KMT2ALMNA | |
| SCHEMBL7841501 | 0.68 | ALDH1A1 (0.58) | ALDH1A1POLBTDP1KMT2ALMNA | |
| SCHEMBL17817475 | 0.68 | ALDH1A1 (0.58) | ALDH1A1POLBTDP1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176220-A | COORDINATION CATALYST | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1979-11-27 | — | — | US | disclosed |
| US-4068063-A | Catalyst composition for ring-opening polymerization of norbornene derivatives and process for polymerizing same | JAPAN SYNTHETIC RUBBER CO., LTD. (JA) | 1978-01-10 | — | — | US | disclosed |