Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acetylcholine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 known ✓ | P20309 | 7/20 | 0.95 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.95 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.95 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.95 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.95 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.95 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.95 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.95 |
| ▸ | HTR1A | P08908 | 2/20 | 0.95 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.95 |
| ▸ | PGR | P06401 | 1/20 | 0.95 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.95 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.95 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.95 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.95 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.95 |
| ▸ | GALR3 | O60755 | 2/20 | 0.91 |
| ▸ | GAA | P10253 | 1/20 | 0.91 |
| ▸ | RAB9A | P51151 | 1/20 | 0.91 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetylcholine SCHEMBL2518957 | 0.97 | CHRM1 (1.00) | CHRM1CHRM3CHRM5CHRM2CHRM4 | |
| Acetylcholine SCHEMBL3216 | 0.97 | CHRM1 (1.00) | CHRM1CHRM3CHRM5CHRM2CHRM4 | |
| Acetylcholine SCHEMBL15687718 | 0.95 | CHRM1 (0.95) | CHRM1CHRM3CHRM5CHRM2CHRM4 | |
| Acetylcholine SCHEMBL8513991 | 0.95 | CHRM1 (0.95) | CHRM1CHRM3CHRM5CHRM2CHRM4 | |
| Acetylcholine SCHEMBL21925712 | 0.95 | CHRM1 (0.95) | CHRM1CHRM3CHRM5CHRM2CHRM4 | |
| Acetylcholine SCHEMBL1899186 | 0.95 | CHRM1 (0.95) | CHRM1CHRM3CHRM5CHRM2CHRM4 | |
| Acetylcholine SCHEMBL18227923 | 0.95 | CHRM1 (0.95) | CHRM1CHRM3CHRM5CHRM2CHRM4 | |
| Acetylcholine SCHEMBL6023859 | 0.95 | CHRM1 (0.95) | CHRM1CHRM3CHRM5CHRM2CHRM4 | |
| Acetylcholine SCHEMBL3904052 | 0.95 | CHRM1 (0.95) | CHRM1CHRM3CHRM5CHRM2CHRM4 | |
| Acetylcholine SCHEMBL40885 | 0.95 | CHRM5 (1.00) | CHRM1CHRM3CHRM5CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122060839-A | Vegetable pesticide residue rapid screening and detecting method | 云浮市云安区农业发展服务中心 | 2026-05-19 | — | — | CN | claimed |
| WO-2025243073-A1 | FORMULATION FOR BIOCONTROL OF INSECT PESTS IN GRAIN STORES | GARCIA ROJAS, CHRISTIAN JAVIER (EC) | 2025-11-27 | — | — | WO | claimed |
| US-20250101490-A1 | METHOD FOR SCREENING ACETYLCHOLINESTERASE INHIBITOR | ACADEMY OF MILITARY MEDICAL SCIENCES (CN) | 2025-03-27 | — | — | US | claimed |
| CN-119224096-A | Multi-pesticide detection method, electrochemical biosensor array and application | 西北大学 | 2024-12-31 | — | — | CN | claimed |
| EP-4467655-A1 | METHOD FOR SCREENING ACETYLCHOLINESTERASE INHIBITOR | Academy of Military Medical Sciences (CN) | 2024-11-27 | — | — | EP | claimed |
| WO-2024201100-A1 | FORMULATION FOR BIOLOGICALLY CONTROLLING INSECT PESTS IN GRAIN STORAGE | GARCIA ROJAS, CHRISTIAN JAVIER (EC) | 2024-10-03 | — | — | WO | claimed |
| CN-117554358-A | Pesticide residue detection card and preparation method and application thereof | 郑州大学 | 2024-02-13 | — | — | CN | claimed |
| WO-2024023390-A1 | NANOSENSOR FOR DETECTING SCOPOLAMINE | UNIVERSITAT POLITÉCNICA DE VALÉNCIA (ES) | 2024-02-01 | — | — | WO | claimed |
| CN-117343923-A | Efficient immobilization method of acetylcholinesterase and organophosphorus pesticide degradation monitoring application | 吉林大学 | 2024-01-05 | — | — | CN | claimed |
| WO-2022111742-A1 | PHARMACEUTICAL COMPOSITION OF NAPHTHALENE DERIVATIVES AS MULTI-TARGET THERAPEUTIC AGENTS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | CENTRO DE NEUROCIENCIAS DE CUBA (CU) | 2022-06-02 | — | — | WO | claimed |
| EP-1724358-A1 | Diagnostic kit for Hirschsprung disease (congenital megacolon) | Martucciello, Giuseppe (IT) | 2006-11-22 | — | — | EP | claimed |
| WO-2006040765-A1 | METHODS AND IMPLANTABLE DEVICES FOR TREATING SUPRAVENTRICULAR ARRHYTHMIAS | CLOSED LOOP THERAPIES LTD. (IL) | 2006-04-20 | — | — | WO | claimed |
| US-20060079941-A1 | Methods and implantable devices for treating supraventricular arrhythmias | CLOSED LOOP THERAPIES LTD. (IL) | 2006-04-13 | — | — | US | claimed |
| EP-1439389-A2 | Method and test kit for the detection of insecticide resistance in insect vectors | Institute for Medical Research (MY) | 2004-07-21 | — | — | EP | claimed |
| CN-1502982-A | Method and kit for testing resistivity of insects to pesticides | ҽҩ�о�Ժ | 2004-06-09 | — | — | CN | claimed |
| US-20040101923-A1 | Method and test kit for the detection of insecticide resistance in insect vectors | INSTITUTE FOR MEDICAL RESEARCH (MY) | 2004-05-27 | — | — | US | claimed |
| EP-0012819-B1 | METHOD FOR FORMING A FILM ADHERING TO A SUBSTRATE AND METHOD FOR WRITING AND ERASING INFORMATION IN A FILM THUS PREPARED | International Business Machines Corporation (US) | 1985-06-12 | — | — | EP | claimed |
| EP-0020974-B1 | ELECTROCHROMIC PRINTING INK DISSOLVED IN WATER AND METHOD FOR PRINTING WITH THIS PRINTING INK | International Business Machines Corporation (US) | 1984-02-08 | — | — | EP | claimed |
| US-4211616-A | Electrochromic printing system | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1980-07-08 | — | — | US | claimed |
| US-4181406-A | Electrochromic display device | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1980-01-01 | — | — | US | claimed |