Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569307 | 0.89 | ADORA3 (0.37) | L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL11567430 | 0.89 | LMNA (0.40) | MAPTL3MBTL1ALDH1A1GLATP53 | |
| SCHEMBL11568582 | 0.87 | HTT (0.45) | KDM4EL3MBTL1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11568178 | 0.85 | ALDH1A1 (0.47) | MAPTKDM4EALDH1A1TP53HPGD | |
| SCHEMBL11566689 | 0.83 | L3MBTL1 (0.46) | MAPTKDM4EL3MBTL1ALDH1A1TP53 | |
| SCHEMBL11567852 | 0.83 | L3MBTL1 (0.42) | MAPTKDM4EL3MBTL1ALDH1A1GLA | |
| SCHEMBL11634918 | 0.80 | L3MBTL1 (0.36) | L3MBTL1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11634094 | 0.78 | HTT (0.44) | MAPTKDM4EL3MBTL1ALDH1A1HPGD | |
| SCHEMBL860192 | 0.77 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11567522 | 0.76 | CNR2 (0.40) | MAPTKDM4EL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002881-A1 | 5-Isoxazolylurea derivatives, their preparation, their use and compositions containing them | FISONS plc (GB) | 1979-07-11 | — | — | EP | disclosed |