Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30168178 | 1.00 | CA1 (0.63) | CA1CA2CA9MAPTKMT2A | |
| SCHEMBL7569526 | 0.87 | HDAC1 (0.52) | CA1CA2CA9MAPTKMT2A | |
| SCHEMBL30641940 | 0.87 | ALDH1A1 (0.58) | CA1CA2CA9MAPTKMT2A | |
| SCHEMBL520441 | 0.87 | ALDH1A1 (0.58) | CA1CA2CA9MAPTKMT2A | |
| SCHEMBL8966015 | 0.84 | NPC1 (0.54) | CA1CA2CA9MAPTHSD17B10 | |
| SCHEMBL628743 | 0.82 | NPC1 (0.66) | CA1CA2CA9MAPTHSD17B10 | |
| SCHEMBL22505690 | 0.82 | MAPT (0.62) | CA1CA2CA9MAPTKMT2A | |
| SCHEMBL29822237 | 0.82 | KDM4E (0.66) | CA1CA2CA9HSD17B10SMN1; SMN2 | |
| SCHEMBL4311940 | 0.82 | KDM4E (0.66) | CA1CA2CA9HSD17B10SMN1; SMN2 | |
| SCHEMBL9400181 | 0.82 | RAB9A (0.63) | CA1CA2CA9MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230141403-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-05-11 | — | — | US | disclosed |
| EP-4161930-A1 | NOVEL IMIDAZO-PYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |
| CN-115667264-A | Novel imidazo-pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |
| WO-2021249893-A1 | NOVEL IMIDAZO-PYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |
| CN-109575463-A | A kind of preparation method of mobile phone screen protector | 李佳峻 | 2019-04-05 | — | — | CN | disclosed |
| CN-102548984-B | The inhibitor of PI3 kinases and/or MTOR | AMGEN INC. (US) | 2015-11-25 | — | — | CN | disclosed |
| EP-2424859-B1 | INHIBITORS OF PI3 KINASE AND / OR MTOR | AMGEN INC (US) | 2015-04-08 | — | — | EP | disclosed |
| CN-102827082-B | Thienopyrazole derivative having PDE7 inhibitory activity | DAIICHI SANKYO CO LTD | 2015-01-07 | — | — | CN | disclosed |
| US-8901315-B2 | Thienopyrazole derivative having PDE7 inhibitory activity | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-12-02 | — | — | US | disclosed |
| US-8772480-B2 | Inhibitors of PI3 kinase and/or mTOR | AMGEN INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-4220586-A | FASTNESS TO LIGHT, OVER-LACQUERING, MIGRATION, WEATHERING, AND HEAT | CIBA-GEIGY CORPORATION (US) | 1980-09-02 | — | — | US | disclosed |
| EP-0014318-A1 | Reactive dyestuffs, their preparation and their use for dyeing materials containing hydroxyl or amide groups | BAYER AG (DE) | 1980-08-20 | — | — | EP | disclosed |
| US-4173646-A | Tricyclicdicarboximides | MERCK & CO., INC. (US) | 1979-11-06 | — | — | US | disclosed |
| US-4132799-A | TRANQUILIZERS, ANTICONVULSANTS | MERCK & CO., INC. (US) | 1979-01-02 | — | — | US | disclosed |
| US-4094636-A | DIAZOTIZATION | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-06-13 | — | — | US | disclosed |
| US-4080321-A | COLORFASTNESS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |
| US-4062838-A | LACQUERS, PRINTING INKS, YELLOW TO ORANGE | CIBA-GEIGY CORPORATION (US) | 1977-12-13 | — | — | US | disclosed |
| US-4061763-A | TRANQUILIZER, ANTICONVULSANT | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4038240-A | PROCESS FOR DYEING POLYURETHANE RESINS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-26 | — | — | US | disclosed |
| US-4006233-A | TRANQUILIZER, ANTICONVULSANT | MERCK & CO., INC. (US) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230141403-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | XDH, MYD88, IKZF3 | CA1 4800/4885CA2 2574/4885CA9 4349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.