Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PGK1 | P00558 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30641940 | 1.00 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MAPK1CA1CA2 | |
| SCHEMBL115706 | 0.87 | CA1 (0.63) | ALDH1A1HSD17B10CA1CA2CA9 | |
| SCHEMBL30168178 | 0.87 | CA1 (0.63) | ALDH1A1HSD17B10CA1CA2CA9 | |
| SCHEMBL11290854 | 0.83 | HSD17B10 (0.56) | ALDH1A1HSD17B10MAPK1CA1CA2 | |
| SCHEMBL28850174 | 0.82 | HDAC1 (0.56) | ALDH1A1HSD17B10MAPK1CA1CA2 | |
| SCHEMBL8966015 | 0.82 | NPC1 (0.54) | ALDH1A1HSD17B10MAPK1CA1CA2 | |
| SCHEMBL9121377 | 0.82 | HSD17B10 (0.52) | ALDH1A1HSD17B10MAPK1KMT2AMEN1 | |
| SCHEMBL1708819 | 0.81 | HDAC1 (0.62) | ALDH1A1MAPK1CA1CA2CA9 | |
| SCHEMBL2388970 | 0.81 | EPHX1 (0.70) | ALDH1A1HSD17B10KMT2AMEN1EPHX1 | |
| SCHEMBL4016123 | 0.81 | MEN1 (0.58) | ALDH1A1HSD17B10MAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240409504-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | DUKE UNIVERSITY | 2024-12-12 | — | — | US | disclosed |
| US-20240343681-A1 | MOLECULES HAVING PESTICIDAL UTILITY AND INTERMEDIATES AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2024-10-17 | — | — | US | disclosed |
| US-20240317727-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | DUKE UNIVERSITY | 2024-09-26 | — | — | US | disclosed |
| US-12098117-B2 | Compositions and methods for the treatment of cancer | DUKE UNIVERSITY (US) | 2024-09-24 | — | — | US | disclosed |
| EP-4313939-A1 | MOLECULES HAVING PESTICIDAL UTILITY AND INTERMEDIATES AND PROCESSES RELATED THERETO | Corteva Agriscience LLC (US) | 2024-02-07 | — | — | EP | disclosed |
| CN-117098750-A | Molecules having pesticidal utility, and intermediates and methods related thereto | 科迪华农业科技有限责任公司 | 2023-11-21 | — | — | CN | disclosed |
| WO-2022204080-A1 | MOLECULES HAVING PESTICIDAL UTILITY AND INTERMEDIATES AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2022-09-29 | — | — | WO | disclosed |
| WO-2022204080-A1 | MOLECULES HAVING PESTICIDAL UTILITY AND INTERMEDIATES AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2022-09-29 | — | — | WO | disclosed |
| US-20220106265-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | DUKE UNIVERSITY (US) | 2022-04-07 | — | — | US | disclosed |
| EP-3894392-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | Duke University (US) | 2021-10-20 | — | — | EP | disclosed |
| WO-2006069788-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2006-07-06 | — | — | WO | disclosed |
| US-20050209213-A1 | Quinoline compound | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-22 | — | — | US | disclosed |
| CN-1585751-A | Quinoline compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-02-23 | — | — | CN | disclosed |
| EP-1447402-A1 | QUINOLINE COMPOUND | Takeda Chemical Industries, Ltd. (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-0425345-B1 | Keratinic fibres dyeing process with amino-indoles, composition and use devices | OREAL (FR) | 1994-09-14 | — | — | EP | disclosed |
| US-5254135-A | Applying indole dye, developing with oxidizing system | L'OREAL (FR) | 1993-10-19 | — | — | US | disclosed |
| CN-1051669-A | With the method for amino indole dyeing keratinous fibres, compositions and facilities and equipments | OREAL (FR) | 1991-05-29 | — | — | CN | disclosed |
| EP-0425345-A1 | Keratinic fibres dyeing process with amino-indoles, composition and use devices | L'OREAL (FR) | 1991-05-02 | — | — | EP | disclosed |
| US-4968784-A | BLACK DYE FOR PAPER | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1990-11-06 | — | — | US | disclosed |
| US-4080321-A | COLORFASTNESS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409504-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | HSF1, HSP90AB1, HSP90AA1 | ALDH1A1 2667/4885HSD17B10 2152/4885MAPK1 2343/4885 |
| US-20240343681-A1 | MOLECULES HAVING PESTICIDAL UTILITY AND INTERMEDIATES AND PROCESSES RELATED THERETO | ACHE, DDT, MLYCD | ALDH1A1 326/4885HSD17B10 1831/4885MAPK1 2624/4885 |
| US-12098117-B2 | Compositions and methods for the treatment of cancer | HSF1, HSP90AB1, HSP90AA1 | ALDH1A1 2667/4885HSD17B10 2152/4885MAPK1 2343/4885 |
| US-20240317727-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | HSF1, HSP90AB1, HSP90AA1 | ALDH1A1 2667/4885HSD17B10 2152/4885MAPK1 2343/4885 |
| US-20220106265-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | HSF1, HSP90AB1, HSP90AA1 | ALDH1A1 2667/4885HSD17B10 2152/4885MAPK1 2343/4885 |
| US-20050209213-A1 | Quinoline compound | MC1R, MC2R, TYR | ALDH1A1 1174/4885HSD17B10 284/4885MAPK1 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.