SCHEMBL11570980

SCHEMBL11570980

Cc1c(OC(=O)O)sc(=O)n1C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11593446 0.76 KDM4E (0.33) ALDH1A1HSD17B10GSK3AGSK3B
SCHEMBL11400363 0.71 KDM4E (0.38) ALDH1A1HSD17B10GSK3AGSK3B
SCHEMBL2075661 0.67 KDM4E (0.43) ALDH1A1HSD17B10GSK3AGSK3B
SCHEMBL4867747 0.66
SCHEMBL5071806 0.61
SCHEMBL4198493 0.60 KMT2A (0.36) ALDH1A1
SCHEMBL11039343 0.58 ALDH1A1 (0.31) ALDH1A1
SCHEMBL486254 0.58 RAB9A (0.39) ALDH1A1
SCHEMBL5238525 0.58 TPMT (0.35) ALDH1A1HSD17B10
SCHEMBL5697079 0.58 CA1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0005204-A2 Plant growth regulating compositions containing 2-thiazolon-5-carboxylic acid derivatives, their preparation and their application BAYER AG (DE) 1979-11-14 EP disclosed