Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385618 | 0.85 | MAPT (0.36) | RAB9ARECQLALDH1A1TSHRNPC1 | |
| SCHEMBL6605939 | 0.83 | CNR1 (0.34) | RAB9ARECQLALDH1A1HPGDTSHR | |
| SCHEMBL5237956 | 0.81 | RAB9A (0.33) | RAB9ARECQLALDH1A1HPGDTSHR | |
| SCHEMBL8964648 | 0.79 | PTGDR2 (0.37) | RAB9ARECQLALDH1A1HPGDTSHR | |
| SCHEMBL10360798 | 0.79 | ALDH1A1 (0.33) | ALDH1A1HPGDTSHR | |
| SCHEMBL11286087 | 0.79 | ALDH1A1 (0.46) | RAB9AALDH1A1HPGDTSHRNPC1 | |
| SCHEMBL3252712 | 0.78 | LMNA (0.38) | RAB9AALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL2428792 | 0.75 | MAPT (0.47) | RAB9AALDH1A1NPC1SMN1; SMN2GAA | |
| SCHEMBL2566875 | 0.75 | KMT2A (0.32) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL9850884 | 0.74 | SMN1; SMN2 (0.36) | ALDH1A1HPGDTSHRSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635567-B1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2015-10-28 | — | — | EP | claimed |
| EP-2411363-B1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER IP GMBH (DE) | 2015-10-07 | — | — | EP | disclosed |
| EP-2411363-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | Bayer Pharma AG (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108608-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-30 | — | — | WO | disclosed |
| EP-0199675-A1 | Heterocyclic penem compounds | CIBA-GEIGY AG (CH) | 1986-10-29 | — | — | EP | disclosed |