Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | FABP2 | P12104 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27406073 | 0.81 | HPGD (0.46) | PPARAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL156135 | 0.78 | HPGD (0.47) | PPARAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL31532258 | 0.77 | MEN1 (0.46) | PPARAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11573102 | 0.77 | CA1 (0.48) | PPARAMEN1KMT2ACYP1A2CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL22437492 | 0.77 | HPGD (0.46) | PPARAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL4592607 | 0.77 | ALOX15 (0.44) | CYP2D6ALOX15TSHRHPGDSRD5A2 | |
| SCHEMBL22468182 | 0.76 | F2 (0.57) | MEN1KMT2AMAPTCYP2C19ALOX15 | |
| SCHEMBL292790 | 0.75 | ELANE (0.53) | PPARAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL28392149 | 0.74 | RXRA (0.47) | MEN1KMT2ACYP1A2CYP2D6MAPT | |
| SCHEMBL1326212 | 0.74 | HPGD (0.43) | PPARAMEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003275-A1 | Aromatic derivatives of phosphonoformic acid, processes for their preparation, pharmaceutical compositions containing them and their use for combating virus infections | Astra Läkemedel Aktiebolag (SE) | 1979-08-08 | — | — | EP | disclosed |