SCHEMBL292790

SCHEMBL292790

O=C(O)Oc1ccc(Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.53
HPGD P15428 1/20 0.52
PPARA Q07869 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C19 P33261 1/20 0.50
LMNA P02545 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
SRD5A2 P31213 1/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.48
TAAR1 Q96RJ0 1/20 0.47
LIPE Q05469 2/20 0.47
PPARG P37231 2/20 0.47
FABP2 P12104 1/20 0.47
SLC22A12 Q96S37 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27467310 0.98 ELANE (0.52) ELANEHPGDPPARAMEN1KMT2A
Hydrochloric Acid SCHEMBL11850724 0.98 ELANE (0.52) ELANEHPGDPPARAMEN1KMT2A
SCHEMBL21991763 0.93 MAOA (0.50) ELANEHPGDPPARAMEN1KMT2A
SCHEMBL6224552 0.93 HSD17B10 (0.50) ELANEHPGDPPARAMEN1KMT2A
SCHEMBL8458974 0.91 ELANE (0.66) ELANEHPGDPPARAMAPTLMNA
Guanidine SCHEMBL7467156 0.89 ELANE (0.46) ELANEHPGDPPARAMEN1KMT2A
SCHEMBL465132 0.87 LMNA (0.52) ELANEMEN1KMT2AMAPTLMNA
SCHEMBL28670578 0.84 LMNA (0.50) ELANEMEN1KMT2AMAPTLMNA
SCHEMBL21992513 0.83 NR4A2 (0.71) MAPTSMN1; SMN2NR4A2
SCHEMBL76135 0.83 LMNA (0.64) ELANEHPGDPPARAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108947797-A A kind of preparation method of chlorine phenoxy carboxylic acid herbicides 山东润博生物科技有限公司 2018-12-07 CN claimed
CN-108947793-A A kind of preparation method of chlorine phenoxy carboxylic acid herbicides 山东润博生物科技有限公司 2018-12-07 CN claimed
EP-2727915-B1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof CONCERT PHARMACEUTICALS INC (US) 2016-04-13 EP claimed
EP-2727915-A1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof Concert Pharmaceuticals Inc. (US) 2014-05-07 EP claimed
US-20110184173-A1 Pyripyropene Derivatives Having An ACAT2-Inhibiting Activity THE KITASATO INSTITUTE (JP) 2011-07-28 US claimed
CN-101965352-A PYRIPYROPENE DERIVATIVE HAVING ACAT2-INHIBITING ACTIVITY KITASATO INST 2011-02-02 CN claimed
EP-2228376-A1 PYRIPYROPENE DERIVATIVE HAVING ACAT2-INHIBITING ACTIVITY The Kitasato Institute (JP) 2010-09-15 EP claimed
EP-4419513-B1 ANTITUMORAL COMPOUNDS PHARMA MAR SA (ES) 2025-08-27 EP disclosed
US-12384800-B2 Antitumoral compounds PHARMA MAR, S.A. (ES) 2025-08-12 US disclosed
US-20250243174-A1 ANTITUMORAL COMPOUNDS PHARMA MAR, S.A. (ES) 2025-07-31 US disclosed
WO-2025077996-A1 SYNTHETIC PROCESS FOR THE MANUFACTURE OF ECTEINASCIDIN COMPOUNDS PHARMA MAR, S.A. (ES) 2025-04-17 WO disclosed
WO-2025050647-A1 IONIZABLE CATIONIC LIPID COMPOUNDS AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 晟迪生物医药(苏州)有限公司 2025-03-13 WO disclosed
US-12215100-B2 Anticancer compounds PHARMA MAR, S.A. (ES) 2025-02-04 US disclosed
EP-0757051-A1 PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME SUNTORY LIMITED (JP) 1997-02-05 EP disclosed
US-5463102-A Process for the continuous production of aryl carbonates BAYER AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed
EP-0638552-A1 PROCESS FOR SYNTHESIZING 4-SUBSTITUTED AZETIDINONE DERIVATIVE SUNTORY LIMITED (JP) 1995-02-15 EP disclosed
US-5344954-A Ester interchange, countercurrent flow in two-stage column reactor BAYER AKTIENGESELLSCHAFT (DE) 1994-09-06 US disclosed
EP-0424800-A2 Polycarbonate IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1991-05-02 EP disclosed
US-4099972-A DIFFUSION TRANSFER MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-07-11 US disclosed
US-3989710-A POSTEMERGENCE HERBICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12384800-B2 Antitumoral compounds TP53, TOP1, MCL1 ELANE 2014/4885HPGD 263/4885PPARA 3930/4885
US-20250243174-A1 ANTITUMORAL COMPOUNDS MCL1, XPOT, GZMB ELANE 1489/4885HPGD 649/4885PPARA 3345/4885
US-20110184173-A1 Pyripyropene Derivatives Having An ACAT2-Inhibiting Activity ACAT2, ACAT1, AGPAT2 ELANE 3470/4885HPGD 1060/4885PPARA 103/4885
US-12215100-B2 Anticancer compounds TP53, MCL1, MYC ELANE 3468/4885HPGD 1265/4885PPARA 3423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.