Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9667981 | 0.87 | MEN1 (0.50) | MEN1KMT2ALMNAMAPTGPR55 | |
| SCHEMBL11082289 | 0.84 | ALDH1A1 (0.38) | MEN1KMT2ALMNAMAPTGPR55 | |
| Ethylenediamine SCHEMBL10384245 | 0.81 | MEN1 (0.45) | MEN1KMT2ALMNAMAPTGPR55 | |
| SCHEMBL4796677 | 0.79 | MEN1 (0.44) | MEN1KMT2ALMNAALDH1A1ESR1 | |
| SCHEMBL8129683 | 0.78 | KIF11 (0.41) | MEN1KMT2ALMNAMAPTGPR55 | |
| SCHEMBL7768805 | 0.78 | MEN1 (0.42) | MEN1KMT2ALMNAMAPTGPR55 | |
| SCHEMBL15171992 | 0.77 | ALDH1A1 (0.33) | MEN1KMT2ALMNAMAPTGPR55 | |
| SCHEMBL15171997 | 0.76 | ALDH1A1 (0.37) | MEN1KMT2ALMNAMAPTGPR55 | |
| SCHEMBL15171994 | 0.76 | ESR1 (0.37) | MEN1KMT2ALMNAMAPTGPR55 | |
| SCHEMBL362964 | 0.74 | TSHR (0.43) | MEN1KMT2AALDH1A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4066709-A | α-Ethyny benzhydrols | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1978-01-03 | — | — | US | claimed |
| US-4094908-A | Alpha-substituted benzhydrol derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1978-06-13 | — | — | US | disclosed |
| US-4082813-A | 3-Ioda-α-ethynyl benzhydrol | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1978-04-04 | — | — | US | disclosed |
| US-4075249-A | 3,4,5-Trimethoxy-α-ethynyl-benzhydrol as a fungicidally effective compound | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1978-02-21 | — | — | US | disclosed |
| US-4066709-A | α-Ethyny benzhydrols | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1978-01-03 | — | — | US | disclosed |
| US-4039589-A | LIVER MICROSOMAL ENZYMES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1977-08-02 | — | — | US | disclosed |
| US-3965179-A | BLOCKING, VIRICIDE, FUNGICIDE | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1976-06-22 | — | — | US | disclosed |