Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112426 | 0.88 | TSHR (0.39) | ALDH1A1GABRA1GABRB2CASRMEN1 | |
| SCHEMBL9667981 | 0.84 | MEN1 (0.50) | ALDH1A1CYP19A1KIF11ESR1ESR2 | |
| SCHEMBL11574346 | 0.84 | MEN1 (0.41) | ALDH1A1CYP19A1KIF11HTR2AHTR2C | |
| SCHEMBL15875002 | 0.83 | CHRM2 (0.37) | ALDH1A1CYP19A1KIF11KDM4EPABPC1 | |
| SCHEMBL15171992 | 0.81 | ALDH1A1 (0.33) | ALDH1A1CYP19A1KDM4EPABPC1APOBEC3A | |
| SCHEMBL362964 | 0.81 | TSHR (0.43) | ALDH1A1KDM4EPABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL18883812 | 0.81 | GABRA1 (0.38) | ALDH1A1GABRA1GABRB2CASRTSHR | |
| SCHEMBL15171994 | 0.79 | ESR1 (0.37) | ALDH1A1CYP19A1KDM4EPABPC1APOBEC3A | |
| SCHEMBL4796677 | 0.78 | MEN1 (0.44) | ALDH1A1KIF11ESR1ESR2MEN1 | |
| SCHEMBL9067519 | 0.78 | KCNN4 (0.52) | ALDH1A1CYP19A1KIF11KDM4EPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131193-A1 | PYRANOQUINAZOLINE DERIVATIVES AND NAPHTHOPYRAN DERIVATIVES | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2020-04-30 | — | — | US | disclosed |
| US-4467102-A | RACEMIC MODIFICATION WITH BRUCINE | UBE INDUSTRIES, LTD. (JP) | 1984-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131193-A1 | PYRANOQUINAZOLINE DERIVATIVES AND NAPHTHOPYRAN DERIVATIVES | PPOX, TYR, NQO1 | ALDH1A1 1152/4885CYP19A1 2177/4885KIF11 1469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.