Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 11/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.30 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531715 | 0.75 | — | — | |
| SCHEMBL11647272 | 0.74 | L3MBTL1 (0.32) | TSHRL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL11570434 | 0.74 | L3MBTL1 (0.32) | TSHRL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL24015835 | 0.69 | ACACB (0.34) | L3MBTL1 | |
| SCHEMBL28660632 | 0.69 | MTNR1A (0.58) | TSHRALDH1A1MTNR1AMTNR1BKMT2A | |
| SCHEMBL514228 | 0.68 | QPCT (0.49) | TSHRALDH1A1MTNR1AMTNR1BQPCT | |
| SCHEMBL179677 | 0.68 | TSHR (0.60) | TSHRALDH1A1MTNR1AMTNR1BKMT2A | |
| SCHEMBL11575203 | 0.67 | MTNR1A (0.35) | MTNR1AMTNR1B | |
| SCHEMBL22023852 | 0.66 | — | — | |
| SCHEMBL16136378 | 0.64 | NPSR1 (0.50) | ALDH1A1MTNR1AQPCTQPCTLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-53141271-A | — | — | None | — | — | JP | disclosed |
| JP-S53141271-A | HETEROCYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | YAMANOUCHI PHARMACEUT CO LTD | 1978-12-08 | — | — | JP | disclosed |