SCHEMBL28660632

SCHEMBL28660632

CC(=O)NCCSC(C)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 11/20 0.58
MTNR1B P49286 11/20 0.58
TSHR P16473 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.41
CASR P41180 1/20 0.41
SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31290509 0.78 MAPT (0.45) MTNR1AMTNR1BTSHRL3MBTL1ALDH1A1
SCHEMBL9866486 0.78 ALDH1A1 (0.56) ALDH1A1MAPTKMT2A
Iodide SCHEMBL9865687 0.77 SLC6A3 (0.33) MTNR1AMTNR1BTSHRL3MBTL1MAPT
SCHEMBL9866492 0.77 NPC1 (0.37) MTNR1AMTNR1BTSHRALDH1A1MAPT
SCHEMBL31290434 0.76 CYSLTR2 (0.50) ALDH1A1MAPT
SCHEMBL31290421 0.75 MAPT (0.50) L3MBTL1ALDH1A1MAPTKMT2ASLC6A3
SCHEMBL31290475 0.74 CA12 (0.49) TSHRALDH1A1MAPTKMT2ASLC6A3
SCHEMBL31290531 0.74 SLC6A3 (0.55) MAPTKMT2ASLC6A3
SCHEMBL4219824 0.74 MTNR1A (1.00) MTNR1AMTNR1BCASR
SCHEMBL31290526 0.74 HPGD (0.51) L3MBTL1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111377841-B Method for inducing asymmetric mercapto-alkene click reaction through chiral inorganic liquid crystal carrier 中国科学技术大学 2021-07-06 CN disclosed
CN-111377841-A Method for inducing asymmetric mercapto-alkene click reaction through chiral inorganic liquid crystal carrier 中国科学技术大学 2020-07-07 CN disclosed