Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28519762 | 0.79 | TDP1 (0.57) | ADRB2ADRB1ADRB3ALDH1A1TDP1 | |
| SCHEMBL14273831 | 0.79 | TDP1 (0.57) | ADRB2ADRB1ADRB3ALDH1A1TDP1 | |
| SCHEMBL3295954 | 0.79 | TDP1 (0.57) | ADRB2ADRB1ADRB3ALDH1A1TDP1 | |
| SCHEMBL9770903 | 0.79 | ADRB2 (0.45) | ADRB2ADRB1ADRB3ALDH1A1MAPT | |
| SCHEMBL27853486 | 0.79 | ALDH1A1 (0.57) | ADRB2ADRB1ADRB3ALDH1A1MAPT | |
| SCHEMBL30318836 | 0.78 | ALDH1A1 (0.53) | ADRB2ADRB1ADRB3ALDH1A1MAPT | |
| Squalane SCHEMBL6425894 | 0.78 | TDP1 (0.56) | ADRB2ADRB1ADRB3ALDH1A1TDP1 | |
| SCHEMBL571219 | 0.78 | ALDH1A1 (0.69) | ADRB2ADRB1ADRB3ALDH1A1MAPT | |
| SCHEMBL28875159 | 0.77 | MAPT (0.56) | ADRB2ADRB1ADRB3ALDH1A1MAPT | |
| SCHEMBL27471367 | 0.77 | ADRB2 (0.68) | ADRB2ADRB1ADRB3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151205-A | Synthesis of vitamin E | HOFFMAN-LA ROCHE INC. (US) | 1979-04-24 | — | — | US | disclosed |