SCHEMBL11575411

SCHEMBL11575411

Cc1ccc(C)c(NC(=O)Nc2c(O)cccc2O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.60
LMNA P02545 1/20 0.60
TSHR P16473 1/20 0.60
HSD17B10 Q99714 1/20 0.60
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA9 Q16790 1/20 0.57
TRPV1 Q8NER1 1/20 0.53
POLB P06746 3/20 0.53
CXCR2 P25025 1/20 0.50
NPC1 O15118 2/20 0.49
TP53 P04637 1/20 0.49
MAPT P10636 1/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C19 P33261 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11648867 0.85 CA12 (0.62) RAB9ALMNATSHRHSD17B10CA12
SCHEMBL11152871 0.79 RAB9A (0.70) RAB9ALMNATSHRHSD17B10POLB
SCHEMBL6566895 0.78 CXCR2 (0.66) RAB9ALMNAHSD17B10POLBCXCR2
SCHEMBL15866574 0.78 CXCR2 (0.69) RAB9ALMNATSHRHSD17B10CXCR2
SCHEMBL25308380 0.76 CNR1 (0.53) RAB9ACA12CA1CA2CA9
SCHEMBL11141270 0.76 LMNA (0.57) RAB9ALMNATSHRHSD17B10POLB
SCHEMBL11400333 0.75 LMNA (1.00) RAB9ALMNATSHRHSD17B10POLB
SCHEMBL2330120 0.75 CA12 (0.56) RAB9ALMNATSHRHSD17B10CA12
SCHEMBL21568041 0.74 GAA (0.66) RAB9ALMNATSHRHSD17B10NPC1
SCHEMBL7651532 0.74 GAA (0.60) RAB9ALMNATSHRHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4126461-A NONDIFFUSIBLE RESORCINOL COUPLER EASTMAN KODAK COMPANY (US) 1978-11-21 US disclosed