Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6314435 | 0.76 | LMNA (0.42) | CYP1A2LMNACYP2C19L3MBTL1CYP2C9 | |
| SCHEMBL480866 | 0.75 | HPGD (0.51) | SMN1; SMN2HPGDALDH1A1CYP1A2LMNA | |
| SCHEMBL17515099 | 0.75 | HTT (0.53) | SMN1; SMN2HPGDGAAL3MBTL1RAB9A | |
| SCHEMBL1499227 | 0.74 | MKNK1 (0.40) | SMN1; SMN2HPGDALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL10589307 | 0.73 | NAAA (0.55) | SMN1; SMN2HPGDALDH1A1LMNAL3MBTL1 | |
| SCHEMBL2066987 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDALDH1A1CYP1A2LMNA | |
| SCHEMBL2069209 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDALDH1A1CYP1A2LMNA | |
| SCHEMBL2069207 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDALDH1A1CYP1A2LMNA | |
| SCHEMBL21994282 | 0.71 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL997166 | 0.71 | GAA (0.72) | SMN1; SMN2HPGDALDH1A1CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139623-A | HYPOTENSIVE AGENTS | C-G CORP. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4027027-A | BETA-RECEPTOR-BLOCKERS, HYPOTENSIVES AND VALODILATORS; FOR TREATING ARRYTHMIAS AND ANGINA PECTORIS | CIBA-GEIGY CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |