Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2527441 | 0.76 | HTR6 (0.33) | HTR6HTR2A | |
| SCHEMBL11574136 | 0.76 | HTR2A (0.36) | HTR6HTR2A | |
| SCHEMBL11038886 | 0.73 | CHRNB4 (0.38) | HTR6HTR2AATM | |
| SCHEMBL9056494 | 0.72 | HTR2A (0.38) | HTR6HTR2A | |
| SCHEMBL8070385 | 0.72 | HTR6 (0.33) | HTR6HTR2AATM | |
| SCHEMBL9568818 | 0.70 | HTR2A (0.32) | HTR2A | |
| SCHEMBL27261195 | 0.69 | HTR2A (0.35) | HTR6HTR2A | |
| SCHEMBL668104 | 0.69 | SIGMAR1 (0.38) | HTR6HTR2A | |
| SCHEMBL6752383 | 0.69 | HTR2A (0.38) | HTR6HTR2A | |
| SCHEMBL8368203 | 0.69 | HTR2A (0.38) | HTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172945-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4138497-A | Indanpentol derivatives for treating hypertension | E. R. SQUIBB & SONS, INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4127578-A | Diene intermediates for indantetrols | E. R. SQUIBB & SONS, INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4092318-A | HYPOTENSIVES | E. R. SQUIBB & SONS, INC. (US) | 1978-05-30 | — | — | US | disclosed |
| US-4053596-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-10-11 | — | — | US | disclosed |
| US-4044040-A | HYPERTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-08-23 | — | — | US | disclosed |