SCHEMBL11575818

SCHEMBL11575818

O=C(OC12CC3CC(CC(C3)C1)C2)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.51
HSP90AA1 P07900 2/20 0.49
CKS1B P61024 1/20 0.49
SKP1 P63208 1/20 0.49
SKP2 Q13309 1/20 0.49
EPHX2 P34913 4/20 0.48
P2RX7 Q99572 1/20 0.47
CYP19A1 P11511 4/20 0.45
TSHR P16473 2/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 1/20 0.45
HTT P42858 1/20 0.45
EPHX1 P07099 1/20 0.45
F2 P00734 1/20 0.45
LMNA P02545 1/20 0.45
CYP17A1 P05093 3/20 0.44
GAA P10253 1/20 0.44
CASR P41180 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30526381 0.93 F2 (0.48) FAAHHSP90AA1CKS1BSKP1SKP2
SCHEMBL17344396 0.90 FAAH (0.45) FAAHHSP90AA1CKS1BSKP1SKP2
SCHEMBL8129733 0.88 HSP90AA1 (0.48) FAAHHSP90AA1CKS1BSKP1SKP2
SCHEMBL685883 0.84 ALDH1A1 (0.56) HSP90AA1CKS1BSKP1SKP2EPHX2
SCHEMBL8134445 0.84 CYP19A1 (0.46) FAAHHSP90AA1CKS1BSKP1SKP2
SCHEMBL6368046 0.83 POLB (0.54) HSP90AA1CKS1BSKP1SKP2EPHX2
SCHEMBL22822742 0.81 HSP90AA1 (0.46) HSP90AA1CKS1BSKP1SKP2KDM4E
SCHEMBL27255740 0.81 RAB9A (0.54) FAAHHSP90AA1CKS1BSKP1SKP2
SCHEMBL26240669 0.81 PDCD1 (0.43) FAAHHSP90AA1CKS1BSKP1SKP2
SCHEMBL28327409 0.80 FAAH (0.46) FAAHEPHX2P2RX7CYP19A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137485-A Process for producing benzoic acid amide compound 爱茉莉太平洋股份有限公司 2018-06-08 CN claimed
CN-102276468-B Resin containing adamantanes, preparation method and application of resin UNIV CHANGZHOU 2013-12-18 CN claimed
CN-102276468-A Resin containing adamantanes, preparation method and application of resin 2011-12-14 CN claimed
US-4142036-A Polyphenylcarboxylic acid adamantane compounds and polymers prepared therefrom STANDARD OIL COMPANY (INDIANA) (US) 1979-02-27 US claimed
EP-4573094-A2 CDK2 INHIBITORS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-06-25 EP disclosed
WO-2025080300-A1 SALT FORMS OF IRAK4 DEGRADERS KYMERA THERAPEUTICS, INC. (US) 2025-04-17 WO disclosed
EP-4447959-A1 METHODS OF TREATING CANCER Kymera Therapeutics, Inc. (US) 2024-10-23 EP disclosed
WO-2024197221-A2 SOLID FORMS OF MDM2 DEGRADERS KYMERA THERAPEUTICS, INC. (US) 2024-09-26 WO disclosed
WO-2024197216-A2 MDM2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2024-09-26 WO disclosed
EP-4334307-A1 CDK2 DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2024-03-13 EP disclosed
WO-2024039903-A2 CDK2 INHIBITORS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2024-02-22 WO disclosed
EP-4319756-A1 CBL-B MODULATORS AND USES THEREOF Nimbus Clio, Inc. (US) 2024-02-14 EP disclosed
CN-105246906-B Process for preparing metal organic compounds 英国贝尔法斯特女王大学 2018-07-31 CN disclosed
CN-108137485-A Process for producing benzoic acid amide compound 爱茉莉太平洋股份有限公司 2018-06-08 CN disclosed
CN-103702977-B Benzoic acid amide compound 株式会社爱茉莉太平洋 2016-08-17 CN disclosed
US-20150241779-A1 REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES OSAKA UNIVERSITY (JP) 2015-08-27 US disclosed
WO-2015125495-A1 Reagent for Enhancing Generation of Chemical Species TOYO GOSEI CO., LTD. (JP) 2015-08-27 WO disclosed
CN-102276468-B Resin containing adamantanes, preparation method and application of resin UNIV CHANGZHOU 2013-12-18 CN disclosed
CN-102276468-A Resin containing adamantanes, preparation method and application of resin 2011-12-14 CN disclosed
US-4142036-A Polyphenylcarboxylic acid adamantane compounds and polymers prepared therefrom STANDARD OIL COMPANY (INDIANA) (US) 1979-02-27 US disclosed