SCHEMBL17344396

SCHEMBL17344396

O=C(OC12CC3CC(C1)CC(OC(=O)c1ccccc1)(C3)C2)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.45
EPHX2 P34913 3/20 0.43
F2 P00734 1/20 0.42
LMNA P02545 1/20 0.42
P2RX7 Q99572 1/20 0.42
GAA P10253 1/20 0.42
HSP90AA1 P07900 1/20 0.41
CKS1B P61024 1/20 0.41
SKP1 P63208 1/20 0.41
SKP2 Q13309 1/20 0.41
TSHR P16473 4/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HTT P42858 1/20 0.40
EPHX1 P07099 1/20 0.40
CHRNA7 P36544 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
DPP8 Q6V1X1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26240669 0.91 PDCD1 (0.43) FAAHHSP90AA1CKS1BSKP1SKP2
SCHEMBL11575818 0.90 FAAH (0.51) FAAHEPHX2F2LMNAP2RX7
SCHEMBL30526381 0.86 F2 (0.48) FAAHEPHX2F2LMNAGAA
SCHEMBL24213064 0.84 POLB (0.48) EPHX2F2LMNAHSP90AA1CKS1B
SCHEMBL26240670 0.82 CES2 (0.44) LMNAHSP90AA1CKS1BSKP1SKP2
SCHEMBL26240810 0.79 HSP90AA1 (0.40) FAAHEPHX2HSP90AA1CKS1BSKP1
SCHEMBL24212971 0.79 NPC1 (0.49) TSHRKMT2AALDH1A1POLB
SCHEMBL8129733 0.78 HSP90AA1 (0.48) FAAHEPHX2LMNAP2RX7HSP90AA1
SCHEMBL17344397 0.76 DPP4 (0.53) EPHX2LMNAP2RX7GAAALDH1A1
SCHEMBL24212719 0.76 MEN1 (0.45) EPHX2HSP90AA1CKS1BSKP1SKP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150362847-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-12-17 US disclosed
US-20150362847-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-12-17 US disclosed