Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | GGT1 | P19440 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313273 | 1.00 | MAPT (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL3137754 | 1.00 | MAPT (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL900182 | 0.88 | KDM4E (0.54) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL900178 | 0.88 | KDM4E (0.54) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL17378062 | 0.88 | KDM4E (0.54) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL27481030 | 0.87 | KDM4E (0.45) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL27481029 | 0.87 | KDM4E (0.45) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Hydrochloric Acid SCHEMBL16993797 | 0.86 | KDM4E (0.52) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL7259702 | 0.84 | KDM4E (0.50) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Ethylene SCHEMBL28132201 | 0.84 | KDM4E (0.50) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688578-B1 | MIA (MELANOMA INHIBITORY ACTIVITY) INHIBITORS FOR PREVENTING AND CURING VITILIGO | BORDIGNON MATTEO (IT) | 2019-03-27 | — | — | EP | claimed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| CN-113316568-A | 2-formyl-3-hydroxyphenyloxymethyl compounds capable of modulating hemoglobin | 全球血液疗法股份有限公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-106316982-B | Thiazine amide derivative and use thereof | 中国人民解放军军事医学科学院毒物药物研究所 | 2020-08-14 | — | — | CN | disclosed |
| US-10335417-B2 | Thiazideamide derivative and use thereof | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2019-07-02 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| US-20180185376-A1 | Thiazideamide Derivative and Use Thereof | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2018-07-05 | — | — | US | disclosed |
| EP-3335720-A1 | C-DI-GMP BINDING PEPTIDES | Universität Basel (CH) | 2018-06-20 | — | — | EP | disclosed |
| EP-3327010-A1 | THIAZIDEAMIDE DERIVATIVE AND USE THEREOF | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China (CN) | 2018-05-30 | — | — | EP | disclosed |
| EP-2889293-B1 | THIAZINE AMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | INST PHARMACOLOGY & TOXICOLOGY ACAD MILITARY MEDICAL SCIENCES PLA CHINA (CN) | 2017-04-26 | — | — | EP | disclosed |
| US-7361711-B2 | Compositions for use in golf balls | ACUSHNET COMPANY (US) | 2008-04-22 | — | — | US | disclosed |
| US-7358309-B2 | core or the layer includes a composition formed from a base polymer, a crosslink initiator, and at least one additive; additive has at least one carbon-oxygen-boron linkage, carbon in the linkage being a secondary or tertiary carbon; enhances coefficient of restitution and/or reduces compression of core | ACUSHNET COMPANY (US) | 2008-04-15 | — | — | US | disclosed |
| US-7358310-B2 | Compositions for use in golf balls | ACUSHNET COMPANY (US) | 2008-04-15 | — | — | US | disclosed |
| US-7358308-B2 | Compositions for use in golf balls | ACUSHNET COMPANY (US) | 2008-04-15 | — | — | US | disclosed |
| US-20060281586-A1 | Compositions for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2006-12-14 | — | — | US | disclosed |
| US-20060281587-A1 | Compositions for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2006-12-14 | — | — | US | disclosed |
| US-20050245657-A1 | Compositions for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-11-03 | — | — | US | disclosed |
| US-20050245652-A1 | Compositions for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-11-03 | — | — | US | disclosed |
| US-4487780-A | SUBSTITUTED CYSTEINE COMPOUNDS | SCHEINBERG ISRAEL H | 1984-12-11 | — | — | US | disclosed |
| US-4315028-A | COPPER OR GOLD COMPLEX OF PENICILLAMINE | SCHEINBERG ISRAEL H | 1982-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10335417-B2 | Thiazideamide derivative and use thereof | TREH, AQP4, TST | MAPT 31/4885KDM4E 2027/4885THRB 1120/4885 |
| US-20180185376-A1 | Thiazideamide Derivative and Use Thereof | TREH, AQP4, TST | MAPT 31/4885KDM4E 2027/4885THRB 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.